If you're planning a visit to St. Louis and need a convenient and comfortable place to stay near University Hospital, you’re in the right spot! I’ve gathered a list of the 15 best hotels that cater to all your needs, whether you’re here for a medical appointment, work, or leisure. Each of these accommodations offers a blend of comfort, accessibility, and great amenities. Let’s dive in and find the perfect hotel for your stay!
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3763 Forest Park Avenue | 0.9 mi (1.4km) to SSM Health Saint Louis University Hospital
If you’re looking for a fantastic place to stay near University Hospital in St. Louis, check out Element St. Louis Midtown! This charming hotel offers comfy accommodation with tons of amenities that’ll make your stay feel a bit like home. Enjoy a delicious American breakfast to kick-start your day and take advantage of free WiFi throughout the building. Feeling active? You can borrow one of the free bikes to explore the area or work up a sweat in the fitness center. And don’t forget to relax in the inviting indoor pool—perfect for unwinding after a long day!
Rooms come with some nice perks, including options with convenient kitchen areas, so you can whip up a quick snack. The hotel also has a lovely restaurant, room service, and friendly staff available 24/7 to ensure everything is just right during your visit. Element St. Louis Midtown offers a delightful blend of comfort and convenience that makes it a great choice for both leisure and business travelers. Enjoy your time in St. Louis and make some wonderful memories!
4245 Duncan Avenue | 1.1 mi (1.8km) to SSM Health Saint Louis University Hospital
If you're searching for a cozy spot near University Hospital, look no further than the Aloft St. Louis Cortex! This fun hotel has a friendly vibe and lots of great features to make your stay wonderful. Dive into a hearty American breakfast to fuel your day, hang out in the shared lounge or on the terrace, and chill out with a drink at the bar. Plus, with an indoor pool and a 24-hour front desk, you’ll have everything you need right at your fingertips.
The rooms are designed with comfort in mind, offering a cozy seating area where you can relax. If you're up for a little fun, feel free to challenge friends or family to a game of billiards. And after a day of exploring St. Louis, you can rest easy knowing you have a comfy retreat waiting for you at Aloft St. Louis Cortex. Enjoy your stay!
525 South Jefferson Avenue | 1.2 mi (1.9km) to SSM Health Saint Louis University Hospital
For a delightful stay near University Hospital, you’ll want to check out the Residence Inn Saint Louis Downtown. This hotel combines comfort and convenience with spacious rooms that feature cozy living areas and fully equipped kitchens. It’s perfect for anyone looking to feel right at home, whether you’re here for a short visit or an extended stay. Plus, brewing your morning coffee with their handy coffee makers is a nice touch to start your day!
When you’re ready to unwind, head over to the onsite snack bar for a refreshing drink or break a sweat in the fitness center. And if you’re in the mood for some local fun, places like Busch Stadium and America’s Center Convention Complex are just a quick drive away. The Residence Inn is the kind of home base that makes your St. Louis adventure easy and enjoyable!
920 South Taylor Avenue | 1.3 mi (2.1km) to SSM Health Saint Louis University Hospital
Home2 Suites St. Louis / Forest Park is a fantastic option for anyone looking to stay near University Hospital. This cozy hotel, nestled in the charming Central West End area, boasts an indoor pool and full kitchens in every room. Each studio is designed for comfort, featuring a flat-screen TV with HBO, a separate seating area, blackout curtains for a good night's sleep, and handy amenities like a hairdryer in the private bathroom.
At Home2 Suites, you can enjoy a bite to eat at the onsite restaurant and keep up with your fitness routine at the well-equipped gym. If you need groceries or laundry services, they’ve got that covered. Whether you're visiting for business or leisure, this friendly spot makes it easy to feel right at home during your stay!
3550 Samuel Shepard Drive | 1.3 mi (2.1km) to SSM Health Saint Louis University Hospital
Ready to explore some great hotels in St. Louis near University Hospital? Angad Arts Hotel is a top choice! Located just a short drive from the hospital, this colorful spot combines art with comfort. Guests can relax in a fitness center, enjoy some evening entertainment, or hang out in the cozy shared lounge. With 24-hour front desk service and a tasty restaurant serving American dishes, there’s no shortage of comfort and convenience.
Each room at Angad Arts is a comfy hangout, complete with a desk for work, a flat-screen TV for entertainment, and a private bathroom. Whether you’re fueling up with breakfast in the morning or unwinding with a drink from the mini-bar in the evening, this hotel is designed to make your stay enjoyable. Plus, if you're looking for dietary-friendly options, they’ve got you covered!
Book your stay at Angad Arts Hotel for a warm welcome and an artsy vibe that will make your trip special!
4215 Lindell Boulevard | 1.4 mi (2.2km) to SSM Health Saint Louis University Hospital
When you're on the lookout for a cozy spot near University Hospital in St. Louis, The West End is a fantastic option to consider! Nestled in Tower Grove, this hotel packs in plenty of great features, including a fitness center, a lovely garden, and a relaxing shared lounge to kick back in after a busy day. Plus, there’s private parking and free WiFi, so you’ll feel right at home right away. Feel like grilling? There’s even a barbecue for those sunny days when you want to cook up something tasty!
The West End’s guest rooms are perfect for unwinding after a long day. Each room is equipped with everything you need—think air conditioning, a handy fridge, a microwave, and of course, a comfy private bathroom. If you're up for some fun, the surrounding Tower Grove area offers plenty of options, like cycling to soak in the local sights. Book your stay at The West End and enjoy a delightful blend of comfort and convenience!
2340 Market Street at Jefferson | 1.5 mi (2.3km) to SSM Health Saint Louis University Hospital
If you're searching for a welcoming place to stay near University Hospital in St. Louis, you’ll want to check out the Courtyard St. Louis Downtown. This hotel offers a fantastic fitness center so you can keep up with your workouts, and you'll love that they provide free Wi-Fi throughout the property. Need a cozy spot to crash? The guest rooms feature comfortable beds, cable TV (with HBO!), and even coffee-making facilities to kickstart your mornings.
Hungry? The hotel’s Bistro serves up delicious breakfast and dinner options, plus you can grab your favorite Starbucks coffee whenever you like. If you're traveling for work, there’s a 24-hour business center ready to help you stay productive. You're just a stone's throw away from local attractions, including the iconic Gateway Arch and the Scottrade Center. The Courtyard is a great choice for a comfortable and enjoyable stay in the heart of St. Louis!
2144 Market Street | 1.6 mi (2.5km) to SSM Health Saint Louis University Hospital
If you're looking for a convenient and cozy hotel near University Hospital in St. Louis, the Fairfield Inn and Suites by Marriott St. Louis Downtown is a great pick! This hotel features air-conditioned rooms perfect for relaxing after a long day. Don’t worry about staying connected—there’s free Wi-Fi and a fitness center to keep you active. Plus, having a 24-hour front desk means you can check in or grab help whenever you need it!
The rooms are equipped with a desk and a flat-screen TV for your entertainment. Each one has a private bathroom complete with a shower and hairdryer, along with storage space for your belongings. Feeling thirsty? Stop by the hotel bar for a drink. Whether you’re here for business or just to explore St. Louis, this hotel offers a comfortable base to recharge and take on the day!
2211 Market Street | 1.6 mi (2.6km) to SSM Health Saint Louis University Hospital
If you're on the hunt for a friendly spot to stay near University Hospital in St. Louis, check out the Pear Tree Inn Saint Louis Union Station. It’s just a short stroll to some great local attractions! Every room is ready for you with a flat-screen TV, free Wi-Fi, and a microwave to heat up snacks, plus a mini fridge for your drinks. Guests can kick start their day with a complimentary breakfast featuring tasty continental treats, perfect for fueling your adventures ahead!
When it comes to relaxing after your explorations, this hotel has you covered. Enjoy a refreshing dip in the indoor pool or unwind in the hot tub. And if you want to break a sweat, the fitness center is right there! With amenities like a launderette and a business center available for all guests, you’ll feel right at home while soaking up the charm of St. Louis.
4550 Forest Park Avenue | 1.6 mi (2.6km) to SSM Health Saint Louis University Hospital
If you’re looking for a great hotel near University Hospital in St. Louis, DoubleTree by Hilton St. Louis Forest Park is a fantastic choice. Just a hop away from Forest Park, this cozy spot features comfy guest rooms with 55" flat-screen TVs and free Wi-Fi, so you can binge-watch your favorite shows or just stay connected. Each room also comes with a fridge, a microwave for quick snacks, and coffee-making facilities so you can sip on your favorite brew anytime. Don’t forget to treat yourself to goodies from the MadeMarket right on site.
After a day of exploring, kick back in the fitness center or head out to nearby attractions like the Saint Louis Science Center and the Saint Louis Zoo, both just a short drive away. Whether you're traveling for work or leisure, DoubleTree by Hilton St. Louis Forest Park offers everything you need for a delightful stay in the heart of the city. It’s the perfect base to enjoy all the charm that St. Louis has to offer!
201 South 20th Street | 1.7 mi (2.7km) to SSM Health Saint Louis University Hospital
If you're hunting for a cozy spot near University Hospital in St. Louis, check out Drury Inn and Suites at Union Station. This hotel gives you a warm welcome with comfy rooms that feature free WiFi and flat-screen TVs—perfect for winding down after a busy day. You'll find a fridge and a microwave in your room too, so whipping up a late-night snack is a breeze. Plus, don’t miss the delicious complimentary hot breakfast each morning, featuring fresh fruit, bagels, pastries, and cereals to fuel your adventures.
There’s plenty to enjoy right on site, like an indoor pool for a refreshing dip and a hot tub for unwinding. If you’re in the mood for some exercise, the fitness center is open 24/7! And when you're ready to explore, you’re just a hop, skip, and jump away from great attractions. So whether you're here for a good time or just passing through, Drury Inn checks all the boxes for a delightful stay in St. Louis.
1820 Market Street | 1.8 mi (2.9km) to SSM Health Saint Louis University Hospital
If you’re looking for charming accommodations near University Hospital in St. Louis, the St. Louis Union Station Hotel is a fantastic choice. Housed in the historic Union Railway Station, this hotel brings the charm of the 19th century to life with stunning Tiffany stained glass in its lobby. Each room is equipped with free Wi-Fi and a 37-inch flat-screen TV, so you can relax and unwind comfortably. With ironing facilities included, you'll always look your best.
Dining options are easy and delicious here! Enjoy upscale American cuisine at the Station Grille Restaurant or sip on cocktails and tasty appetizers at the Grand Hall Lounge. If you’re up for a quick bite, Einstein Bros Bagels has you covered for breakfast and lunch. Plus, there’s an outdoor pool and fitness center, making it easy to stay active during your trip. All in all, St. Louis Union Station Hotel provides a delightful stay with easy access to local attractions.
4630 Lindell Boulevard | 1.8 mi (2.9km) to SSM Health Saint Louis University Hospital
If you’re on the lookout for a great place to stay near University Hospital in St. Louis, the Holiday Inn Express St. Louis Central West End is a fantastic option. Just a quick stroll from the beautiful Forest Park, it’s perfect for stretching your legs and enjoying nature. The hotel features cozy rooms with comfy beds, a flat-screen TV for entertainment, and all the essentials like a fridge and coffee maker to start your day right.
Every morning, the hotel serves up a tasty buffet breakfast—perfect fuel for your adventures! Plus, there’s a fitness center for those who like to keep active during their travels. With convenient business facilities on-site, this hotel has everything you need for both work and play. Enjoy the charm of St. Louis while staying at this lovely hotel!
215 York Avenue | 2 mi (3.1km) to SSM Health Saint Louis University Hospital
If you're searching for a wonderful spot to stay near University Hospital in St. Louis, the AC Hotel by Marriott St Louis Central West End is a great pick. This hotel offers a cozy environment with air-conditioned rooms that include comfortable seating areas, flat-screen TVs, and coffee machines to kickstart your morning. Plus, you'll find a bar and a tasty restaurant right on-site to relax and enjoy your meals.
To keep your energy up, an American breakfast is served every morning. Don't forget to check out the shared lounge or the fitness center if you’re looking to squeeze in a workout during your stay. With friendly faces at the 24-hour front desk and all the essentials at your fingertips, your time at the AC Hotel will surely be delightful!
212 North Kingshighway Boulevard | 2 mi (3.2km) to SSM Health Saint Louis University Hospital
If you’re on the hunt for a fantastic place to stay close to University Hospital in St. Louis, the Royal Sonesta Chase Park Plaza is the perfect choice. Nestled right across from the beautiful Forest Park, this hotel is all about comfort and fun. Enjoy an assortment of dining options, like the upscale Tenderloin Room or the relaxed ambiance of The Chase Club, where you can dine indoors or out by the gorgeous Mediterranean-style pool. Plus, there’s a cinema just in case you’re in the mood for a movie night!
Your stay here doesn’t just revolve around great food. Dive into a heated outdoor pool, unwind by the outdoor fireplace, or get your sweat on at the gym. The cozy rooms come equipped with satellite TV and Wi-Fi, ensuring you stay connected and entertained. The Royal Sonesta Chase Park Plaza is all about making your visit enjoyable, with friendly staff ready to make you feel right at home. Enjoy your St. Louis adventure!
Dan, a digital nomad with 10+ years of experience, has traveled to 55+ countries, sharing expert tips to help others find the best places to stay.
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Post was updated on May 15, 2025
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