If you're planning to attend SPIE Optics + Photonics 2025 in San Diego from August 3-7, finding the perfect hotel can make your trip even better. From luxurious stays to cozy retreats, I've curated a list of the 15 top hotels nearby that cater to various tastes and budgets. Whether you want quick access to the event or to enjoy beautiful ocean views, these accommodations have it all. Let’s dive into the options that will make your visit comfortable and enjoyable!
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675 L Street | 0.1 mi (0.2km) to San Diego Convention Center
Planning your stay for the SPIE Optics + Photonics 2025 in San Diego? The Omni San Diego Hotel is the perfect spot to blend comfort and fun. Just a short stroll away, you’ll find a sparkling outdoor pool and a soothing spa to help you unwind after a busy day. Each guest room comes decked out with cozy pillow-top mattresses, fluffy towels, and a comfy vibe. Whether it’s day or night, you can grab a bite at one of the on-site restaurants before diving into some of that sweet San Diego sunshine!
If you’re looking to kick back or meet up with friends, check out Ace Porter, which offers delicious drinks and a rich atmosphere perfect for socializing. The Tortuga Pool Bar serves up tasty food and refreshing cocktails until 6 p.m.—ideal for hanging out by the pool. Whether you're in town for business or simply to enjoy the vibrant city life, Omni San Diego Hotel has everything you need for a relaxing stay.
207 5th Avenue | 0.1 mi (0.2km) to San Diego Convention Center
Looking for a fun and lively place to stay during SPIE Optics + Photonics 2025 in San Diego? Check out the Hard Rock Hotel! This modern gem is right in the heart of the Gaslamp district and comes packed with cool features like a rooftop pool and a buzzing nightlife. Plus, you can borrow a free guitar to jam out during your stay—how cool is that?
Inside, the rooms are bright and contemporary with flat-screen TVs and free Wi-Fi to keep you connected. After a day exploring the city, grab a drink at Float by the rooftop pool or enjoy some delicious sushi at the Nobu restaurant. Maryjane's serves up tasty American dishes round-the-clock, ensuring you're fueled up for more adventures. The vibe here is electric, making it the perfect spot to unwind and soak in the San Diego scene!
1 Park Boulevard | 0.2 mi (0.3km) to San Diego Convention Center
Looking for a great place to stay during the SPIE Optics + Photonics 2025 in San Diego? Consider the Hilton San Diego Bayfront! This waterfront hotel is perfectly positioned next to the San Diego Convention Center and offers stunning views of the bay. Slide into the outdoor pool, relax in one of the hot tubs, or let the kids splash around in their very own Kid’s Splash Zone. With poolside dining options like The Pool Club and Odysea Lounge, you can enjoy yummy bites without straying far from the water.
Step into a cozy room equipped with a flat-screen TV, coffee machine, and a welcoming vibe. For a tasty experience, check out Hudson & Nash Waterfront Kitchen and Cocktails, where California coastal cuisine takes center stage. Enjoy delicious shareable plates made with fresh ingredients while sipping on local craft beers, all while soaking in those gorgeous waterfront views. The cheerful atmosphere, along with friendly staff, makes this place feel like a little piece of San Diego paradise!
660 K Street | 0.2 mi (0.3km) to San Diego Convention Center
The San Diego Marriott Gaslamp Quarter is a fantastic choice for anyone attending the SPIE Optics + Photonics 2025. Just a short stroll away from PETCO Park, this hotel is a great spot to relax after a busy day of events. Unwind at the Altitude Sky Lounge, where you can enjoy breathtaking views and refreshing drinks. Your room will be your cozy retreat, complete with a flat-screen LCD TV, a CD player, and easy internet access to stay connected.
When you're ready to explore, you'll find popular attractions like the San Diego Zoo and Belmont Park just a quick drive away. It’s all about enjoying the local vibe! Whether you're traveling for business or pleasure, the friendly atmosphere and convenient location will make your stay memorable.
356 6th Avenue | 0.2 mi (0.4km) to San Diego Convention Center
The Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter is perfect for anyone attending SPIE Optics + Photonics 2025. This hotel offers a cheerful vibe and cozy rooms, complete with kitchenettes for easy meal prep. Every morning starts with a delightful full American breakfast, so fuel up before heading to your event! Relax at the rooftop pool and enjoy free WiFi during your downtime.
Good news for pet lovers—this is a pet-friendly hotel! You can unwind at Bar Vie, which has both indoor and outdoor seating, perfect for a casual meal or refreshing drink. Need a late-night snack? The 24-hour market has you covered. Plus, with a gym and business center available, you can keep up with your routine or catch up on work before enjoying the nearby attractions. Nearby, you'll find the bustling Gaslamp Quarter, along with landmarks like Petco Park, just a hop, skip, and jump away!
550 J Street | 0.3 mi (0.4km) to San Diego Convention Center
Looking for a fantastic place to stay during SPIE Optics + Photonics 2025? Check out Pendry San Diego! Just a short stroll from the convention center, this stylish hotel has everything you need for a comfy stay. Relax by the outdoor pool, hit the fitness center, or grab a bite at the on-site restaurant. Plus, there's a hot tub waiting for you to soak your cares away.
You'll find loads of great attractions nearby, like the San Diego Maritime Museum and Balboa Park, perfect for some fun in your downtime. The friendly staff is ready to help with tips on where to go and what to do in the area. Whether you've got a busy schedule or want to kick back and relax, Pendry San Diego is the right choice.
435 Sixth Avenue | 0.3 mi (0.5km) to San Diego Convention Center
If you're heading to San Diego for SPIE Optics + Photonics 2025, the Margaritaville Hotel San Diego Gaslamp Quarter is a lively spot you won't want to miss! Right in the heart of the Gaslamp Quarter, this hotel offers a refreshing rooftop pool and a cozy lounge—perfect for unwinding after a busy day at the conference. You can choose from various spacious rooms, some of which even come with spa baths and city views. Each room is equipped with a 55-inch flat-screen TV, a handy charging station, and plush bathrobes for your comfort.
The hotel isn't just about relaxation; it’s also got a fitness center for those who want to keep active during their stay. After a productive day, you can take a short stroll to visit PETCO Park or explore the San Diego Convention Center, both just minutes away. The Margaritaville Hotel makes for a cheerful and convenient base, so you can enjoy both your conference and the exciting city of San Diego!
453 6th Avenue | 0.3 mi (0.5km) to San Diego Convention Center
If you’re planning to attend SPIE Optics + Photonics 2025 in San Diego, check out the Courtyard by Marriott San Diego Downtown/Gaslamp Quarter—a great place to relax and recharge! Just a hop away from some fantastic shops and restaurants, this hotel features a charming on-site bar and restaurant. You’ll enjoy free WiFi in your cozy room, equipped with a flat-screen HDTV and a handy coffee machine to keep you energized.
When you’re ready to unwind after a day of conference fun, grab a bite at the Bistro or sip a cocktail at The Nolen, the hotel’s rooftop bar with stunning views of San Diego Bay. With a business center and bike rentals available, it’s easy to combine work and play here. A friendly 24-hour front desk is always around to help with any needs, ensuring your stay is smooth and enjoyable!
311 Island Avenue | 0.3 mi (0.5km) to San Diego Convention Center
If you’re headed to San Diego for the SPIE Optics + Photonics 2025 conference, the Horton Grand Hotel is a charming spot to consider! Nestled in the lively Gaslamp Quarter, this hotel invites you to stroll through lovely blocks filled with beautiful Victorian architecture and fun shops. Each room is cozy and invites you to relax with a gas-burning fireplace, period furnishings, and even cable TV for your entertainment. Select rooms even offer a balcony where you can take in charming courtyard or city views.
Hungry? Check out Salt & Whiskey, the hotel’s restaurant that serves up delicious dishes alongside live entertainment on the weekends. Whether you're in the mood for a nightcap at the bar or a late-night snack from the gift shop (open 24 hours!), there’s something to satisfy your cravings. Plus, you’ll be just a short drive from famous attractions, like Balboa Park and the San Diego Zoo, adding a bit of adventure to your stay!
521 6th Ave | 0.4 mi (0.6km) to San Diego Convention Center
If you're on your way to San Diego for the SPIE Optics + Photonics 2025 conference, Staypineapple, Hotel Z, Gaslamp San Diego should be on your list! This pet-friendly hotel welcomes you and your furry buddy with open arms. You’ll find free WiFi throughout the property, making it easy to share your conference highlights or plan your day. Rooms are comfy and equipped with flat-screen TVs, so you can kick back and enjoy some downtime after a busy day. Plus, some rooms even come with a cute little seating area to relax!
Need a bike? You're in luck! Guests can borrow bicycles for free, so you can easily explore the nearby sights, like the vibrant Gaslamp Quarter and Horton Plaza Shopping Center—just a short walk away. The 24-hour reception team is here to help with anything you need, ensuring your stay is smooth and enjoyable. Whether you're prepping for your conference or hitting up the local scene, this hotel makes for a great home base!
Fourth Avenue 536 | 0.4 mi (0.6km) to San Diego Convention Center
If you're gearing up for the SPIE Optics + Photonics 2025 conference in San Diego, this accommodation is a fantastic choice! Nestled right in the heart of the city, this spot offers cozy, air-conditioned rooms with free WiFi, plus the bonus of free private parking. With everything from the San Diego Convention Center to popular attractions just a hop, skip, and jump away, it’s the perfect launchpad for your adventures.
Each room is designed for your comfort, featuring a TV, a kitchen for those late-night snacks, and a private bathroom equipped with all the essentials. Whether you're unwinding after a busy day or gearing up for your next conference session, this place has what you need. You can also easily visit the iconic Balboa Park and explore the famous San Diego Zoo nearby, making it a great spot to blend business with a little fun!
Fourth Avenue 536 | 0.4 mi (0.6km) to San Diego Convention Center
If you're headed to San Diego for the SPIE Optics + Photonics 2025 conference, make yourself at home at this accommodation. This great hotel offers inviting, air-conditioned rooms with free WiFi and private parking—all set in the vibrant Gaslamp Quarter. It's an ideal spot for both work and play, with the San Diego Convention Center just a short walk away, and famous attractions like the USS Midway Museum and Maritime Museum just minutes away.
Inside, you'll find cozy living spaces equipped with all the goodies—fridge, oven, and kitchen essentials, along with comfy beds and private bathrooms. It’s the perfect place to kick back after a busy day, recharge, and maybe even whip up a snack or two. Plus, you’re close to Balboa Park and the world-renowned San Diego Zoo if you want to mix in a bit of adventure with your stay!
333 West Harbor Drive | 0.4 mi (0.6km) to San Diego Convention Center
If you're attending the SPIE Optics + Photonics 2025 conference, you’ll love the San Diego Marriott Marquis and Marina. This 4-star hotel is right in downtown San Diego, with stunning views of the waterfront and the bay. Unwind after a busy day in the outdoor pool or hot tub, or treat yourself at the on-site spa. Plus, you’re just a quick stroll away from the San Diego Convention Center, making it super convenient for all your conference activities.
The rooms at this hotel are fresh and modern, featuring everything you need for a comfortable stay, including flat-screen TVs, mini-fridges, and coffee machines. Hungry? Enjoy delicious options right within the hotel—from Asian fusion dishes at Roy’s to hearty American fare at the Marina Kitchen. And for your caffeine fix, there’s a Starbucks on site, too! You can also break a sweat at the 24-hour gym, which offers fitness classes to keep you energized.
If you’re in the mood to explore, you’re in luck! Nearby attractions include Seaport Village and Balboa Park, as well as the famous San Diego Zoo. This hotel is not just a place to stay; it’s your gateway to the fun and excitement of San Diego!
552 5th Avenue | 0.4 mi (0.6km) to San Diego Convention Center
If you’re heading to the SPIE Optics + Photonics 2025 conference, check out the Marin Hotel in the lively Gaslamp Quarter of San Diego. This charming spot offers comfy self-service apartments that come with everything you need to feel right at home, including climate control, cozy dining and workspaces, and handy kitchenettes. Each unit also features a TV for your entertainment and a bathroom with spacious showers, fluffy towels, hairdryers, and complimentary toiletries.
After a long day of learning at the conference, unwind and whip up a snack in your kitchen equipped with a stove top, microwave, and even a coffee machine. Plus, with attractions like Balboa Park and the San Diego Zoo nearby, you can treat yourself to city adventures whenever you want. Whether you’re relaxing in your stylish apartment or stepping out to explore, the Marin Hotel makes for a perfect home base during your San Diego stay.
509 9th Avenue | 0.4 mi (0.7km) to San Diego Convention Center
If you're planning to attend the SPIE Optics + Photonics 2025 conference, the perfect spot to stay is Hotel Indigo in the heart of the Gaslamp District. This vibrant hotel provides cozy guest rooms with a contemporary twist. You can kick back and enjoy the stylish décor paired with practical amenities, plus you’ll find a restaurant right on-site for those times when you don’t feel like heading out.
After exploring all that San Diego has to offer, return to your room where plush bedding and hardwood floors await. Unwind with your favorite show on the flat-screen TV or stay connected with free Wi-Fi. Don’t forget to check out Phi Bar & Bistro for tasty breakfast options or a comforting dinner while soaking in stunning views of the city.
Whether you need to tackle some work at the business center or just wish to relax in a welcoming atmosphere, Hotel Indigo has everything to make your stay enjoyable and comfortable!
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Dan, a digital nomad with 10+ years of experience, has traveled to 55+ countries, sharing expert tips to help others find the best places to stay.
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Post was updated on May 1, 2025
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