Find the best hotels near your favorite destinations Image

15 Best Hotels in San Antonio near Medical Drive

Visiting San Antonio for medical reasons? Choosing the right hotel near Medical Drive makes all the difference. After analyzing dozens of properties, I've found accommodations that combine convenience with comfort, putting you close to healthcare facilities while still enjoying San Antonio's unique charm. My research revealed 15 exceptional hotels that offer everything from shuttle services to quiet recovery spaces. I compared amenities, accessibility features, and guest feedback to compile this list of places where you can rest easy while focusing on health matters. Each offers something special to support your San Antonio medical visit.

Choose your dates:

Sort:

Our Pick

La Quinta by Wyndham San Antonio Medical Ctr. NW

La Quinta by Wyndham San Antonio Medical Ctr. NW

Welcome Inn

7500 Louis Pasteur Drive | 0.4 mi (0.7km) to Medical Dr

7.8Good
Welcome Inn ImageWelcome Inn ImageWelcome Inn Image

Conveniently located in San Antonio's Medical Center district, Welcome Inn offers comfortable, air-conditioned rooms with free WiFi and flat-screen TVs. The 3-star hotel provides 24-hour front desk service and easy access to attractions like Six Flags Fiesta Texas and The Alamo.

Courtyard By Marriott San Antonio Medical Center

8585 Marriott Drive | 0.5 mi (0.8km) to Medical Dr

8.4Very Good
Courtyard by Marriott San Antonio Medical Center ImageCourtyard by Marriott San Antonio Medical Center ImageCourtyard by Marriott San Antonio Medical Center Image

Courtyard San Antonio Medical Center combines convenience and comfort with spacious rooms, free WiFi, and essential in-room amenities including refrigerators and microwaves. The beautifully landscaped property features an outdoor swimming pool and fitness center, while The Bistro serves cooked-to-order breakfasts. Adjacent to South Texas Medical Center, the hotel provides ideal accommodation for medical visitors and professionals.

La Quinta By Wyndham San Antonio Medical Ctr. NW

4431 Horizon Hill Boulevard | 0.9 mi (1.4km) to Medical Dr

8.3Very Good
La Quinta by Wyndham San Antonio Medical Ctr. NW ImageLa Quinta by Wyndham San Antonio Medical Ctr. NW ImageLa Quinta by Wyndham San Antonio Medical Ctr. NW Image

Located just off I-10 near Medical Drive, La Quinta Inn & Suites offers comfortable rooms with flat-screen TVs and free WiFi. Guests enjoy a complimentary hot breakfast buffet, outdoor pool, and convenient access to Six Flags Fiesta Texas and The Alamo.

Fairfield By Marriott Inn & Suites San Antonio Medical Center

7203 Wurzbach Road | 1.1 mi (1.8km) to Medical Dr

8.7Excellent
Fairfield by Marriott Inn & Suites San Antonio Medical Center ImageFairfield by Marriott Inn & Suites San Antonio Medical Center ImageFairfield by Marriott Inn & Suites San Antonio Medical Center Image

Perfectly positioned near Medical Drive, this 3-star Fairfield by Marriott offers a complete package with free parking, outdoor pool, and fitness center. Guests enjoy continental or American breakfast options daily, plus convenient business facilities and free bikes for exploring San Antonio's attractions.

Drury Inn & Suites San Antonio Northwest Medical Center

9806 Interstate Highway 10 West | 1.4 mi (2.2km) to Medical Dr

9Exceptional
Drury Inn & Suites San Antonio Northwest Medical Center ImageDrury Inn & Suites San Antonio Northwest Medical Center ImageDrury Inn & Suites San Antonio Northwest Medical Center Image

Located steps from San Antonio's Medical Center, Drury Inn & Suites offers complimentary hot breakfast and evening refreshments. Guests enjoy well-appointed rooms with flat-screen TVs and refreshment centers, plus convenient amenities including an indoor pool, spa tub, and fitness center with wall-mounted TVs.

San Antonio Marriott Northwest Medical Center

3233 Northwest Loop 410 | 1.5 mi (2.3km) to Medical Dr

8.3Very Good
San Antonio Marriott Northwest Medical Center ImageSan Antonio Marriott Northwest Medical Center ImageSan Antonio Marriott Northwest Medical Center Image

Conveniently located off Interstate 410 near Medical Drive, Marriott Northwest offers spacious rooms with custom-made beds and flat-screen TVs. The hotel features a complimentary shuttle service, outdoor pool, and fitness center, plus easy access to San Antonio's top attractions including the River Walk and The Alamo.

SpringHill Suites By Marriott San Antonio Medical Center/Northwest

3636 Northwest Loop 410 | 1.6 mi (2.6km) to Medical Dr

8.6Excellent
SpringHill Suites by Marriott San Antonio Medical Center/Northwest ImageSpringHill Suites by Marriott San Antonio Medical Center/Northwest ImageSpringHill Suites by Marriott San Antonio Medical Center/Northwest Image

SpringHill Suites Medical Center/Northwest offers spacious suites with living areas, flat-screen TVs, and kitchen amenities just one mile from Texas Medical Center. Guests enjoy convenient access to downtown San Antonio and SeaWorld while taking advantage of the outdoor pool and 24-hour business center.

The Westin San Antonio North

9821 Colonnade Boulevard | 1.7 mi (2.7km) to Medical Dr

8.4Very Good
The Westin San Antonio North ImageThe Westin San Antonio North ImageThe Westin San Antonio North Image

The Westin San Antonio North combines luxury with convenience, featuring both indoor and outdoor pools, the American cuisine restaurant Bolo's, and a lobby bar with live entertainment. Comfortable rooms come equipped with Wi-Fi and coffee makers, while the hotel's prime Medical Drive location provides easy access to the Riverwalk, Sea World, and Six Flags.

Sonesta ES Suites San Antonio Northwest Medical Center

4320 Spectrum One | 1.7 mi (2.8km) to Medical Dr

7.9Good
Sonesta ES Suites San Antonio Northwest Medical Center ImageSonesta ES Suites San Antonio Northwest Medical Center ImageSonesta ES Suites San Antonio Northwest Medical Center Image

Located adjacent to San Antonio Medical Center, Sonesta ES Suites offers spacious all-suite accommodations with full kitchens and free WiFi. Guests enjoy a complimentary hot breakfast buffet each morning, plus convenient amenities including an outdoor pool, fitness center, and barbecue pavilion.

Homewood Suites By Hilton San Antonio Northwest

4323 Spectrum One | 1.8 mi (2.8km) to Medical Dr

8.5Excellent
Homewood Suites by Hilton San Antonio Northwest ImageHomewood Suites by Hilton San Antonio Northwest ImageHomewood Suites by Hilton San Antonio Northwest Image

Offering spacious all-suite accommodations with full kitchens and separate living areas, this San Antonio hotel provides free hot breakfast, Wi-Fi, and parking near Medical Drive. The convenient location puts guests minutes from South Texas Medical Center, USAA Headquarters, and attractions like Six Flags Fiesta Texas, while an outdoor pool and sports court provide on-site relaxation.

Hyatt Place San Antonio Northwest/Medical Center

4303 Hyatt Place Drive | 1.9 mi (3km) to Medical Dr

7.9Good
Hyatt Place San Antonio Northwest/Medical Center ImageHyatt Place San Antonio Northwest/Medical Center ImageHyatt Place San Antonio Northwest/Medical Center Image

Perfectly positioned near the Medical Center, Hyatt Place San Antonio offers spacious rooms with separate living areas, flat-screen TVs, and free Wi-Fi. Guests enjoy convenient amenities including a complimentary shuttle service, on-site Starbucks, and self-service kiosks, all just minutes from USAA and Six Flags Fiesta Texas.

TownePlace Suites By Marriott San Antonio Northwest

5014 Prue Road | 2.3 mi (3.7km) to Medical Dr

7.6Good
TownePlace Suites by Marriott San Antonio Northwest ImageTownePlace Suites by Marriott San Antonio Northwest ImageTownePlace Suites by Marriott San Antonio Northwest Image

TownePlace Suites by Marriott offers fully-equipped kitchens and a complimentary American breakfast near San Antonio's Medical District. The hotel features an outdoor pool, fitness center, and barbecue area, all within easy reach of attractions like Six Flags Fiesta Texas and The Shops at La Cantera.

Holiday Inn Express & Suites San Antonio Medical Center North, An IHG Hotel

11010 Highway I-10 West | 2.4 mi (3.9km) to Medical Dr

7.4Good
Holiday Inn Express & Suites San Antonio Medical Center North, an IHG Hotel ImageHoliday Inn Express & Suites San Antonio Medical Center North, an IHG Hotel ImageHoliday Inn Express & Suites San Antonio Medical Center North, an IHG Hotel Image

Holiday Inn Express and Suites San Antonio combines convenience and comfort near Medical Drive with an outdoor pool and 42 flat-screen TVs in every room. Free hot breakfast, guest laundry, and ample parking make this an ideal base for visiting Six Flags Fiesta Texas and University of Texas San Antonio.

Hampton Inn & Suites San Antonio Northwest/Medical Center

11426 IH 10 West | 2.6 mi (4.2km) to Medical Dr

8.1Very Good
Hampton Inn & Suites San Antonio Northwest/Medical Center ImageHampton Inn & Suites San Antonio Northwest/Medical Center ImageHampton Inn & Suites San Antonio Northwest/Medical Center Image

Just minutes from Six Flags and SeaWorld, Hampton Inn & Suites Northwest/Medical Center offers studio suites with mini-fridges and separate living areas. Guests enjoy daily breakfast, free Wi-Fi, indoor pool, and convenient access to Medical Drive and the University of Texas at San Antonio.

Days Inn By Wyndham San Antonio Near Fiesta Park

11790 Interstate 10 West | 3.1 mi (5km) to Medical Dr

7.8Good
Days Inn by Wyndham San Antonio Near Fiesta Park ImageDays Inn by Wyndham San Antonio Near Fiesta Park ImageDays Inn by Wyndham San Antonio Near Fiesta Park Image

Conveniently located near Medical Drive, this comfortable hotel offers well-equipped rooms with microwaves, refrigerators, free WiFi, and cable TV. Guests enjoy complimentary breakfast items daily, an outdoor pool, free parking, and easy access to Six Flags Fiesta Texas and South Texas Medical Center.

Olga Melnikova's profile

Olga Melnikova

Olga, a hospitality graduate with 10+ years of experience in hotels and travel blogging, has explored Europe extensively and shares expert travel insights.

Please note that we earn a commission when you book through our affiliate links. Your support is greatly appreciated and helps us continue to grow our business. Thank you for being a part of our journey.

Post was updated on June 6, 2025

Did you stay at one of the hotels listed here? We always appreciate hearing from our customers. If you would like to connect with us and share your experience, please feel free to reach out to us directly. right here.