Orlando is a playground of science, adventure, and endless excitement! Get ready to explore this incredible destination with our carefully curated hotel list that puts you minutes from the must-visit Science Center. I've handpicked hotels that offer comfort, convenience, and incredible value for every traveler, ensuring your Orlando experience is as seamless as it is memorable.
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2416 North Orange Avenue | 0.3 mi (0.5km) to Orlando Science Center
Centrally located near Orlando Science Center, this Comfort Suites offers convenient downtown access with modern amenities like a complimentary hot breakfast, outdoor pool, and free WiFi. Spacious rooms feature flat-screen TVs, microwaves, and mini-fridges, complemented by on-site fitness and business centers for comfortable and productive stays.
60 South Ivanhoe Boulevard | 1.1 mi (1.8km) to Orlando Science Center
Situated in downtown Orlando, this contemporary DoubleTree by Hilton offers well-appointed rooms with flat-screen cable TVs, refrigerators, and coffee facilities. The hotel provides convenient amenities including a business center and laundry services, positioning guests just minutes from key Orlando attractions like the Dr. Phillips Center and Camping World Stadium.
730 North Magnolia Avenue | 1.4 mi (2.2km) to Orlando Science Center
Courtyard by Marriott Orlando Downtown offers contemporary comfort with its spacious rooms, outdoor pool, and 24-hour fitness center just steps from downtown's vibrant attractions. Guests enjoy free WiFi, a stylish restaurant, and convenient amenities like room service and a business center, making it an ideal urban retreat near Church Street Station and major Orlando landmarks.
680 North Orange Avenue | 1.5 mi (2.4km) to Orlando Science Center
Located in downtown Orlando, this Residence Inn offers stylish studio and suite accommodations with fully equipped kitchens, perfect for extended stays near local attractions. The hotel provides convenient amenities including a fitness center, indoor pool, complimentary breakfast buffet, and free bikes for exploring the vibrant city center.
304 West Colonial Drive | 1.7 mi (2.7km) to Orlando Science Center
Strategically positioned in Downtown Orlando, this modern hotel offers spacious rooms with fully equipped kitchenettes, a 55 flat screen, and stunning city views just steps from top entertainment venues. With a full-service Bite Bistro & Wine Bar, heated outdoor pool, state-of-the-art fitness center, and complimentary shuttle service, guests enjoy ultimate convenience and comfort in the heart of the city.
401 North Magnolia Avenue | 1.8 mi (2.9km) to Orlando Science Center
Home2 Suites by Hilton offers modern, well-equipped rooms with desks and fridges, perfect for travelers seeking comfort in downtown Orlando. Located near Church Street Station and Kia Center, this 3-star hotel provides convenient amenities including free WiFi, a shared lounge, and a buffet breakfast, making it an ideal stay for business and leisure travelers.
401 North Magnolia Avenue | 1.8 mi (2.9km) to Orlando Science Center
Located in downtown Orlando, this Hilton Garden Inn offers modern comfort with convenient amenities like free WiFi, a restaurant serving American cuisine, and flexible dining options including vegetarian and vegan meals. Guests can unwind in the shared lounge or enjoy 24-hour front desk service and on-site private parking near key attractions like Church Street Station and Kia Center.
227 North Eola Drive | 1.8 mi (3km) to Orlando Science Center
Centrally located in Downtown Orlando, the EO Inn offers stylish rooms with free WiFi, complimentary coffee, and a convenient walk to Lake Eola Park and Thornton Park's vibrant restaurants and boutiques. Guests enjoy easy access to Disney World and Interstate 4, with free parking and grab-and-go breakfast options that make exploring Orlando effortless.
307 South Park Avenue | 1.9 mi (3.1km) to Orlando Science Center
Nestled in historic Winter Park, this charming hotel offers comfortable rooms with cable TV and en suite bathrooms, just steps from Park Avenue's upscale shops and restaurants. Convenient amenities include free WiFi, continental breakfast, 24-hour front desk, and easy access to local attractions like the Morse Museum and Universal Studios.
300 East New England Avenue | 2 mi (3.2km) to Orlando Science Center
The Alfond Inn offers elegant rooms with modern amenities, including a refrigerator, cable TV, and iPod docking station, situated in the charming Winter Park neighborhood near cultural attractions. Hamilton's Kitchen serves exceptional southern cuisine in a sophisticated setting, complemented by the hotel's fitness center, business facilities, and convenient proximity to Park Avenue's shopping and dining.
400 West Livingston Street | 2 mi (3.3km) to Orlando Science Center
Located in downtown Orlando, this Marriott offers modern rooms with flat-screen TVs, streaming services, and in-room coffee facilities, plus convenient access to entertainment venues like the Amway Center. The hotel features a 24-hour fitness center, pool, and 17,000 square feet of meeting space, with dining options including Shades Bar and Grill and in-room meal service.
191 East Pine Street | 2.2 mi (3.5km) to Orlando Science Center
Embassy Suites by Hilton Orlando Downtown offers spacious suites with refrigerators and microwaves, complemented by a free cooked-to-order breakfast and nightly manager's reception. Located in the city center, the hotel provides easy access to major attractions like Universal Orlando Resort, Walt Disney World, and the Kia Center, with an inviting outdoor pool and state-of-the-art fitness center.
1275 Lee Road | 2.3 mi (3.7km) to Orlando Science Center
Nestled in Winter Park, this Hilton Garden Inn offers comfortable rooms with modern amenities, a welcoming restaurant, and a fitness center perfect for business and leisure travelers. Conveniently located near Orlando's top attractions like Church Street Station and Camping World Stadium, the hotel provides free WiFi, 24-hour front desk service, and a delicious daily breakfast buffet.
333 South Garland Avenue | 2.4 mi (3.8km) to Orlando Science Center
Sleek downtown Orlando hotel with contemporary Spanish-inspired design features air-conditioned rooms, a vibrant restaurant, and a stylish rooftop terrace just steps from Church Street Station. AC Hotel by Marriott offers professional travelers modern amenities like free WiFi, a fitness center, and flat-screen TVs, with convenient proximity to key Orlando attractions including Universal Studios and Florida Mall.
325 South Orange Avenue | 2.4 mi (3.9km) to Orlando Science Center
Located in Orlando's vibrant Arts District, the Grand Bohemian Hotel dazzles with its luxurious velvet-draped rooms, rooftop pool offering stunning city panoramas, and the AAA Four-Diamond Boheme Restaurant serving prime steaks and fresh seafood. Just steps from the Dr. Phillips Center for the Performing Arts, this Autograph Collection hotel combines elegant design, live entertainment at the Bosendorfer Lounge, and premium amenities like marble bathrooms and a state-of-the-art fitness center.
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Dan, a digital nomad with 10+ years of experience, has traveled to 55+ countries, sharing expert tips to help others find the best places to stay.
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Post was updated on June 29, 2025
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