Orlando welcomes medical travelers with incredible hotel options near Regional Medical Center! I've carefully curated this list to help you find the perfect home base during your hospital stay or medical visit. These hotels offer comfort, convenience, and peace of mind when you need it most, ensuring you're just minutes away from top-quality healthcare while enjoying a restful environment.
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51 Columbia Street | 0.1 mi (0.2km) to Orlando Regional Medical Center
TownePlace Suites offers comfortable extended-stay accommodations with smart amenities like free bikes, an outdoor swimming pool, and a fitness centre just steps from Orlando's vibrant downtown. Located near Church Street Station with free WiFi and a convenient shared lounge, this 3-star property provides travelers with a convenient and well-equipped home base for exploring the city.
1315 South Orange Avenue | 0.1 mi (0.2km) to Orlando Regional Medical Center
The Delaney Hotel offers modern, well-equipped rooms with amenities like mini-fridges, flat-screen TVs, and private bathrooms, situated conveniently near Church Street Station and key Orlando attractions. With on-site dining featuring American and international cuisine, a fitness center, free WiFi, and 24-hour multilingual staff, this hotel provides comfortable accommodations for business and leisure travelers.
43 Columbia Street | 0.1 mi (0.2km) to Orlando Regional Medical Center
Hampton Inn & Suites offers convenient downtown Orlando accommodation with modern rooms featuring flat-screen TVs, small refrigerators, and free WiFi. Located near Amway Center and Church Street Station, the hotel provides a continental breakfast, business center, and fitness facilities for medical professionals and travelers.
211 N LUCERNE CIR | 0.6 mi (1km) to Orlando Regional Medical Center
Sonder Wellborn offers modern, air-conditioned rooms with terraces, flat-screen TVs, and convenient amenities like coffee machines and private bathrooms just steps from Orlando's vibrant downtown. Built in 2020, this 3-star hotel provides easy access to Church Street Station, Camping World Stadium, and Universal Studios attractions, making it an ideal urban base for travelers.
500 South Orange Avenue | 0.7 mi (1.1km) to Orlando Regional Medical Center
Aloft Orlando Downtown offers a modern, vibrant experience with sleek rooms featuring lake or pool views, an on-site WXYZ bar, and convenient access to Orlando's top attractions like the Amway Center and Walt Disney World. With a 24-hour fitness center, outdoor pool, and free Wi-Fi, this urban hotel provides a comfortable and stylish base for exploring the city.
325 South Orange Avenue | 0.8 mi (1.3km) to Orlando Regional Medical Center
Nestled in Orlando's vibrant Arts District, the Grand Bohemian Hotel dazzles with its rooftop pool, luxurious velvet-draped rooms, and AAA Four-Diamond Boheme Restaurant serving prime steaks and fresh seafood. Just steps from the Dr. Phillips Center for the Performing Arts, this Autograph Collection hotel combines sophisticated design, live entertainment at the Bosendorfer Lounge, and top-tier amenities like a state-of-the-art fitness center.
333 South Garland Avenue | 0.9 mi (1.4km) to Orlando Regional Medical Center
Located in downtown Orlando, AC Hotel offers contemporary Spanish-inspired design with sleek rooms, a vibrant restaurant, and a rooftop terrace just steps from Church Street Station. Guests can enjoy modern amenities like free WiFi, a fitness center, and convenient access to major Orlando attractions including Universal Studios and Florida Mall.
191 East Pine Street | 1 mi (1.7km) to Orlando Regional Medical Center
Embassy Suites by Hilton Orlando Downtown offers spacious suites with refrigerators and microwaves, complemented by a complimentary cooked-to-order breakfast and nightly manager's reception. Located minutes from Orlando's top attractions like Universal Orlando Resort and Walt Disney World, the hotel features a modern fitness center and inviting outdoor pool for relaxed and convenient city stays.
227 North Eola Drive | 1.4 mi (2.3km) to Orlando Regional Medical Center
This downtown boutique hotel offers comfortable rooms with free WiFi, complimentary coffee, and convenient access to Lake Eola Park and Thornton Park's vibrant restaurant district. Located minutes from Disney World and Interstate 4, the EO Inn provides easy parking and grab-and-go breakfast options for travelers seeking a well-positioned Orlando accommodation.
400 West Livingston Street | 1.4 mi (2.3km) to Orlando Regional Medical Center
Situated in downtown Orlando, this Marriott hotel offers modern rooms with flat-screen TVs, streaming services, and in-room amenities like mini-fridges and coffee makers. The property features 17,000 square feet of meeting space, a 24-hour fitness center, an on-site restaurant and bar, and convenient access to local attractions like the Amway Center and Dr. Phillips Center for the Performing Arts.
401 North Magnolia Avenue | 1.5 mi (2.4km) to Orlando Regional Medical Center
Centrally located near Church Street Station, this modern Home2 Suites offers comfortable, well-equipped rooms with desks and fridges, plus a convenient continental breakfast. The 3-star hotel provides free WiFi, a shared lounge, and on-site private parking, making it an ideal choice for travelers seeking comfort and convenience in downtown Orlando.
401 North Magnolia Avenue | 1.5 mi (2.4km) to Orlando Regional Medical Center
Located in downtown Orlando, this Hilton Garden Inn offers modern comfort with a 24-hour front desk, free WiFi, and an on-site American restaurant serving vegetarian and vegan options. The hotel provides convenient access to Church Street Station and Kia Center, with private parking and a welcoming shared lounge perfect for business and leisure travelers.
304 West Colonial Drive | 1.8 mi (2.9km) to Orlando Regional Medical Center
Perfectly situated in Downtown Orlando, this modern hotel offers spacious rooms with premium amenities like fully equipped kitchenettes, flat-screen TVs, and complimentary shuttle service within a 3-mile radius. Guests can enjoy fine dining at Bite Bistro & Wine Bar, relax by the heated outdoor pool, and take advantage of the state-of-the-art fitness center and 24-hour business center.
680 North Orange Avenue | 1.8 mi (2.9km) to Orlando Regional Medical Center
Residence Inn by Marriott Orlando Downtown offers spacious, kitchen-equipped rooms and convenient amenities including a fitness center, indoor pool, and complimentary breakfast just steps from downtown Orlando. With free WiFi, private parking, and a welcoming terrace, this hotel provides comfortable accommodations near Church Street Station and key Orlando attractions.
730 North Magnolia Avenue | 1.9 mi (3km) to Orlando Regional Medical Center
Located in downtown Orlando, Courtyard by Marriott offers modern comfort with its outdoor pool, 24-hour fitness center, and well-appointed rooms featuring flat-screen TVs and private bathrooms. Guests can enjoy on-site dining, a shared lounge, and convenient proximity to Church Street Station and Camping World Stadium.
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Dan, a digital nomad with 10+ years of experience, has traveled to 55+ countries, sharing expert tips to help others find the best places to stay.
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Post was updated on June 28, 2025
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