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8 Best Hotels in Orlando near Medical City

Hey there, medical professionals and travelers! Orlando's Medical City Drive area offers some seriously awesome hotel options that'll make your stay comfortable and convenient. I've carefully researched these top 8 hotels to help you find the perfect home base near your medical destination. Whether you're visiting for work, treatment, or supporting a loved one, these hotels understand exactly what you need – proximity, comfort, and reliability.

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Our Pick

Lake Nona Wave Hotel

Lake Nona Wave Hotel

Residence Inn By Marriott Orlando Lake Nona

6955 Lake Nona Boulevard | 0.6 mi (1km) to Medical City Drive

9.6Exceptional
Residence Inn by Marriott Orlando Lake Nona ImageResidence Inn by Marriott Orlando Lake Nona ImageResidence Inn by Marriott Orlando Lake Nona Image

Nestled in Lake Nona, this modern Residence Inn offers spacious suites with fully-equipped kitchenettes, perfect for extended medical stays near Orlando's medical district. Guests can unwind at the year-round outdoor pool, stay fit in the 24/7 fitness center, and enjoy complimentary amenities like WiFi and barbecue facilities.

Amenities

Safety deposit box
Meeting/banquet facilities
Business centre
Fitness centre

Nearby

Florida Mall
Lakefront Park
Eagle Creek Golf Club
Back to Nature Wildlife Refuge

Important Info

Parking available
Free WiFi throughout
Pets allowed (on request)
Family friendly

Courtyard By Marriott Orlando Lake Nona

6955 Lake Nona Boulevard | 0.7 mi (1.2km) to Medical City Drive

9Exceptional
Courtyard by Marriott Orlando Lake Nona ImageCourtyard by Marriott Orlando Lake Nona ImageCourtyard by Marriott Orlando Lake Nona Image

Nestled in the Lake Nona medical district, this modern Courtyard by Marriott offers convenient amenities including free bikes, an outdoor pool, fitness center, and on-site restaurant. Travelers appreciate its proximity to medical facilities and quick access to Orlando's top attractions, with comfortable rooms and free WiFi providing a perfect home base for business or leisure.

Amenities

Fitness centre
Dry cleaning
Laundry
Restaurant

Nearby

Florida Mall
Lakefront Park
Eagle Creek Golf Club
North Shore Golf Club

Important Info

Parking available
Free WiFi throughout
No pets allowed
Family friendly

Lake Nona Wave Hotel

6100 Wave Hotel Drive | 0.7 mi (1.2km) to Medical City Drive

9.2Exceptional
Lake Nona Wave Hotel ImageLake Nona Wave Hotel ImageLake Nona Wave Hotel Image

Lake Nona Wave Hotel offers a vibrant 4-star experience with modern, air-conditioned rooms, a fitness center, and a stunning sun terrace with a swimming pool. Guests enjoy diverse dining options featuring American, Caribbean, and Mediterranean cuisine, with vegetarian and vegan selections, complemented by convenient room service and a welcoming shared lounge.

Amenities

1 swimming pool
Non-smoking rooms
Fitness centre
Facilities for disabled guests

Nearby

Florida Mall
Lakefront Park
Eagle Creek Golf Club
North Shore Golf Club

Important Info

Parking: USD 40/day
Free WiFi throughout
Pets allowed (charges apply)
Family friendly

Aloft Orlando Lake Nona

7215 Corner Drive | 1.2 mi (1.9km) to Medical City Drive

9.4Exceptional
Aloft Orlando Lake Nona ImageAloft Orlando Lake Nona ImageAloft Orlando Lake Nona Image

Aloft Orlando Lake Nona offers a contemporary design with vibrant, tech-forward spaces and a lively atmosphere, featuring an outdoor pool, American restaurant, and 24-hour fitness center perfect for medical professionals and travelers. Conveniently located near major Orlando attractions like Gatorland and SeaWorld, this hotel provides free WiFi, evening entertainment, and a stylish bar for relaxing after a long day.

Amenities

1 swimming pool
Non-smoking rooms
Fitness centre
Restaurant

Nearby

Florida Mall
Lakefront Park
Eagle Creek Golf Club
North Shore Golf Club

Important Info

Parking available
Free WiFi in rooms
Pets allowed (charges apply)
Family friendly

SpringHill Suites By Marriott Orlando Lake Nona

13700 Boggy Creek Rd. | 1.4 mi (2.2km) to Medical City Drive

9.2Exceptional
SpringHill Suites by Marriott Orlando Lake Nona ImageSpringHill Suites by Marriott Orlando Lake Nona ImageSpringHill Suites by Marriott Orlando Lake Nona Image

SpringHill Suites offers modern comfort with free bikes, an outdoor pool, and a shared terrace just minutes from Medical City. Guests enjoy a buffet breakfast, business center, and contemporary 3-star accommodations near Florida Mall and SeaWorld attractions.

Amenities

1 swimming pool
Non-smoking rooms
Fitness centre
Facilities for disabled guests

Nearby

Florida Mall
SeaWorld Orlando
Walk N Sticks Golf Club
Imperial Golf Club

Important Info

Parking available
Family friendly

Hampton Inn Orlando Southeast Nona

10002 Eagle Creek Sanctuary Blvd | 2.8 mi (4.5km) to Medical City Drive

9.1Exceptional
Hampton Inn Orlando Southeast Nona ImageHampton Inn Orlando Southeast Nona ImageHampton Inn Orlando Southeast Nona Image

Hampton Inn Orlando Southeast offers comfortable rooms with free WiFi and parking, conveniently located near Medical City and major Orlando attractions like Florida Mall and SeaWorld. Guests enjoy a complimentary American breakfast and easy access to central Orlando's top destinations.

Amenities

Lift
24-hour front desk
Fitness
Air conditioning

Nearby

Florida Mall
Lakefront Park
Eagle Creek Golf Club
Back to Nature Wildlife Refuge

Important Info

Parking: USD 10/day
Free WiFi available
Pets allowed (charges apply)
Family friendly

Home2 Suites Orlando Southeast Nona

10002 Eagle Creek Sanctuary Blvd. | 2.8 mi (4.5km) to Medical City Drive

9Exceptional
Home2 Suites Orlando Southeast Nona ImageHome2 Suites Orlando Southeast Nona ImageHome2 Suites Orlando Southeast Nona Image

Home2 Suites Orlando Southeast Nona offers comfortable, fully-equipped suites with kitchens, free WiFi, and an outdoor swimming pool near Medical City. Travelers enjoy convenient amenities like a fitness center, free parking, and American breakfast in this modern 3-star hotel just minutes from SeaWorld and Florida Mall.

Amenities

Fitness
Designated smoking area
Shared lounge/TV area
Smoke alarms

Nearby

Florida Mall
Lakefront Park
Eagle Creek Golf Club
Back to Nature Wildlife Refuge

Important Info

Parking: USD 10/day
Free WiFi available
Pets allowed (charges apply)
Family friendly

Holiday Inn Express & Suites - Orlando - Southeast, An IHG Hotel

10115 William Carey Drive | 3.1 mi (4.9km) to Medical City Drive

8.7Excellent
Holiday Inn Express & Suites - Orlando - Southeast, an IHG Hotel ImageHoliday Inn Express & Suites - Orlando - Southeast, an IHG Hotel ImageHoliday Inn Express & Suites - Orlando - Southeast, an IHG Hotel Image

Conveniently located near Medical City, this Holiday Inn Express offers modern comfort with free WiFi, an outdoor pool, and fitness center for travelers seeking convenience and relaxation. Guests can enjoy non-smoking rooms, 24-hour front desk service, and easy access to Orlando attractions like Gatorland and SeaWorld.

Amenities

Air conditioning
Business centre
Non-smoking throughout
Fax/photocopying

Nearby

Florida Mall
Gatorland
Eagle Creek Golf Club
North Shore Golf Club

Important Info

Parking available
Free WiFi throughout
No pets allowed
Family friendly
Dan Avramescu's profile

Dan Avramescu

Dan, a digital nomad with 10+ years of experience, has traveled to 55+ countries, sharing expert tips to help others find the best places to stay.

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Post was updated on July 3, 2025

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