Hey there, medical professionals and travelers! Orlando's Medical City Drive area offers some seriously awesome hotel options that'll make your stay comfortable and convenient. I've carefully researched these top 8 hotels to help you find the perfect home base near your medical destination. Whether you're visiting for work, treatment, or supporting a loved one, these hotels understand exactly what you need – proximity, comfort, and reliability.
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6955 Lake Nona Boulevard | 0.6 mi (1km) to Medical City Drive
Nestled in Lake Nona, this modern Residence Inn offers spacious suites with fully-equipped kitchenettes, perfect for extended medical stays near Orlando's medical district. Guests can unwind at the year-round outdoor pool, stay fit in the 24/7 fitness center, and enjoy complimentary amenities like WiFi and barbecue facilities.
6955 Lake Nona Boulevard | 0.7 mi (1.2km) to Medical City Drive
Nestled in the Lake Nona medical district, this modern Courtyard by Marriott offers convenient amenities including free bikes, an outdoor pool, fitness center, and on-site restaurant. Travelers appreciate its proximity to medical facilities and quick access to Orlando's top attractions, with comfortable rooms and free WiFi providing a perfect home base for business or leisure.
6100 Wave Hotel Drive | 0.7 mi (1.2km) to Medical City Drive
Lake Nona Wave Hotel offers a vibrant 4-star experience with modern, air-conditioned rooms, a fitness center, and a stunning sun terrace with a swimming pool. Guests enjoy diverse dining options featuring American, Caribbean, and Mediterranean cuisine, with vegetarian and vegan selections, complemented by convenient room service and a welcoming shared lounge.
7215 Corner Drive | 1.2 mi (1.9km) to Medical City Drive
Aloft Orlando Lake Nona offers a contemporary design with vibrant, tech-forward spaces and a lively atmosphere, featuring an outdoor pool, American restaurant, and 24-hour fitness center perfect for medical professionals and travelers. Conveniently located near major Orlando attractions like Gatorland and SeaWorld, this hotel provides free WiFi, evening entertainment, and a stylish bar for relaxing after a long day.
13700 Boggy Creek Rd. | 1.4 mi (2.2km) to Medical City Drive
SpringHill Suites offers modern comfort with free bikes, an outdoor pool, and a shared terrace just minutes from Medical City. Guests enjoy a buffet breakfast, business center, and contemporary 3-star accommodations near Florida Mall and SeaWorld attractions.
10002 Eagle Creek Sanctuary Blvd | 2.8 mi (4.5km) to Medical City Drive
Hampton Inn Orlando Southeast offers comfortable rooms with free WiFi and parking, conveniently located near Medical City and major Orlando attractions like Florida Mall and SeaWorld. Guests enjoy a complimentary American breakfast and easy access to central Orlando's top destinations.
10002 Eagle Creek Sanctuary Blvd. | 2.8 mi (4.5km) to Medical City Drive
Home2 Suites Orlando Southeast Nona offers comfortable, fully-equipped suites with kitchens, free WiFi, and an outdoor swimming pool near Medical City. Travelers enjoy convenient amenities like a fitness center, free parking, and American breakfast in this modern 3-star hotel just minutes from SeaWorld and Florida Mall.
10115 William Carey Drive | 3.1 mi (4.9km) to Medical City Drive
Conveniently located near Medical City, this Holiday Inn Express offers modern comfort with free WiFi, an outdoor pool, and fitness center for travelers seeking convenience and relaxation. Guests can enjoy non-smoking rooms, 24-hour front desk service, and easy access to Orlando attractions like Gatorland and SeaWorld.
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Dan, a digital nomad with 10+ years of experience, has traveled to 55+ countries, sharing expert tips to help others find the best places to stay.
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Post was updated on July 3, 2025
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