15 Top Hotels in Mission Bay San Francisco

LUMA Hotel San Francisco is making waves as one of the hottest new spots to stay in Mission Bay! Located a short walk from the iconic Oracle Park, this stylish 4-star hotel offers everything you need for a comfy getaway. Enjoy a workout at the fitness center, dine on delicious meals at the restaurant, or just kick back with a drink at the bar. Plus, with free WiFi and attentive service around the clock, you’ll feel right at home.

Every room is equipped with air conditioning and a handy desk, perfect for getting a little extra work done or planning your San Francisco adventures. It’s all about making your stay enjoyable, whether you're in town for a game, exploring local sights, or just escaping for some fun. If you’re on the hunt for a standout place to stay while enjoying the vibrant Mission Bay area, LUMA Hotel is definitely worth checking out!

Hotel Via is one of the top picks in Mission Bay, offering a stylish and modern retreat for guests. Just steps away from Oracle Park, this hotel features all sorts of perks like a rooftop bar that boasts incredible views of the park, the Bay, and the signature San Francisco skyline. Picture yourself sipping a cocktail while soaking in that beautiful scenery! Each room comes with a flat-screen TV and all the essentials like free toiletries—perfect for a cozy stay.

The hotel isn’t just about comfy rooms; it also has a fitness center to get your sweat on, a breakfast café to kickstart your day, and a welcoming communal workspace. With high-speed WiFi throughout, you can easily stay connected. Whether you're here for a ballgame, exploring the unique sights of San Francisco, or just enjoying a weekend away, Hotel Via is a fantastic choice that will make your visit unforgettable.

Hyatt Place San Francisco/Downtown is a fantastic spot to stay in Mission Bay, just a quick stroll from Oracle Park. This 3-star hotel has everything you need for a comfy getaway, including a fitness center, shared lounge, and a lovely terrace where you can unwind. The staff is friendly and available 24/7, ready to assist you at any time. Plus, there’s free WiFi to keep you connected, and a cozy bar for that evening drink!

When you settle into your room, you'll find air conditioning and a sleek flat-screen TV, along with a refrigerator for your snacks. The bathrooms are stocked with free toiletries and a hairdryer, making it easy to feel right at home. Start your mornings off right with a delicious breakfast featuring buffet, continental, and American options, ensuring you’re fueled up for a day of exploring San Francisco. Whether you’re planning a fun day out or just want to relax, Hyatt Place is a great choice for your Mission Bay adventure!

Welcome to one of the best hotels in Mission Bay, San Francisco! Our cozy downtown spot is perfect for your next adventure. You’ll be just a short walk from the excitement of the Moscone Center, beautiful Yerba Buena Gardens, and tons of fascinating museums. If you're a foodie or a shopaholic, you won’t have to wander far to find amazing restaurants and shops. Don’t forget to unwind at our rooftop lounge, where you can sip on handcrafted drinks and enjoy the city views.

Each room at Canopy by Hilton San Francisco SoMa is designed for relaxation. The sliding door panels separate the dressing area from the bedroom, offering a comfy space to get ready for your day. You’ll love the rainfall shower head next to your ergonomic bed and a 42-inch flat-screen TV for those quiet nights in. For a little pick-me-up, visit our Bean Bar for breakfast or grab something quick to go. If you're in the mood for something refreshing, the Mezzanine offers tasty cocktails and wines to indulge in. We can’t wait to make your stay a memorable one!

Looking for a great spot to stay in Mission Bay, San Francisco? The Clancy, part of the Autograph Collection, is a fabulous choice! Nestled in the lively SoMa area, this hotel is surrounded by cool museums and tech hubs. You’ll love wandering through the vibrant local art displayed throughout the property—it's the perfect backdrop for new discoveries and captivating stories.

At The Clancy, there's something for everyone. Whether you're traveling with family, a furry friend, or for business, you’ll find a welcoming atmosphere that feels just right. Relax on the outdoor Block 9 Patio, grab a bite at Seven Square Taproom, or break a sweat in the fitness center. Plus, with top attractions like Oracle Park close by, your days will be packed with fun. Come enjoy San Francisco like never before!

InterContinental San Francisco offers a fantastic stay that puts you right in the heart of the action! With a modern vibe and comfy rooms, this hotel makes your visit to the city an absolute delight. The stylish accommodations are loaded with handy perks, like flat-screen TVs and coffee machines ready to brew your morning pick-me-up. You can also kick back with a snack from the in-room minibar before heading out to explore.

When you’re not soaking up the city sights, the hotel has awesome amenities to enjoy. Stay fit in the 24-hour gym or take a refreshing dip in the indoor lap pool. Don’t miss out on the lovely on-site restaurant, Luce, or grab a drink at Bar 888 after a day full of adventures. Whether you're here for work or fun, you’ll find everything you need for a wonderful stay near top spots like Moscone Convention Center and Chinatown.

The W San Francisco is a fun spot right in the heart of the city's hip SOMA district, surrounded by cool art, lively events, and a buzzing nightlife. Guests will enjoy comfy rooms with modern designs, featuring flat-screen TVs, WiFi, and a Bluetooth speaker alarm clock with handy USB ports—perfect for charging up your devices. Each room comes with a minibar stocked with tasty local snacks and California wines, plus a Nespresso machine with coffee capsules replenished daily to kickstart your mornings.

For dining, Trace offers delicious farm-to-table dishes each night, and the Living Room Bar is a great place to mingle over crafted cocktails. If you're looking to stay active, the bright FIT gym has everything you need for a good workout. With its exciting atmosphere and top-notch amenities, the W San Francisco is a fantastic choice for anyone ready to dive into the city life!

The St. Regis San Francisco shines bright in the vibrant SOMA District. Each guest room is designed with comfort in mind, featuring a flat-screen TV and a relaxing soaking tub, so you can unwind after your day's adventures. There's also a minibar stocked with goodies to satisfy your cravings. Just a short stroll away, you’ll find Union Square, buzzing with shopping and entertainment.

Dining at the hotel is a delightful experience. Astra restaurant serves tasty breakfast, lunch, and dinner, while The St. Regis Bar is the perfect spot to sip on signature cocktails and enjoy a relaxed ambiance. Plus, stepping out, you’re right across the street from the lovely Yerba Buena Gardens, making it easy to soak up the sun and enjoy some outdoor fun. The St. Regis is more than just a place to stay; it's an inviting spot to relax and recharge while you explore all that Mission Bay has to offer!

The Hampton Inn San Francisco Downtown/Convention Center is a fantastic spot for your stay in Mission Bay. It’s all about comfort and convenience here! Each room comes with comfy seating, a cable TV, and a private bathroom complete with a bath or shower. Plus, you can enjoy complimentary WiFi throughout the hotel, so staying connected is a breeze. Kickstart your day with a delicious free breakfast before stepping out to explore San Francisco.

You’ll also find friendly services like a 24-hour reception and luggage storage for your convenience. Getting around is easy and you’re close to many attractions and fun activities. Whether you’re traveling for business or pleasure, this hotel is a great home base for adventuring in the heart of the city!

The Pickwick Hotel in Mission Bay is a great choice for anyone looking to enjoy a fun and relaxing stay in San Francisco! Just a short stroll away from shopping and dining, this hotel combines cozy comfort with a welcoming atmosphere. Every guest room is designed for relaxation, featuring bright colors, free WiFi, cable TV, a fridge, and a handy coffee maker. You can count on all the essentials, whether you’re unwinding after a day of sightseeing or gearing up for your next adventure.

When hunger strikes, you won't have to go far! The hotel boasts two delightful dining options: SOMA Bar & Restaurant and Zevi cafe, where tasty Italian and Mediterranean dishes await. Plus, if you need to squeeze in a workout or get some work done, the fitness and business facilities are right there for you. With friendly staff to help you, The Pickwick Hotel ensures you'll have a splendid stay in the bustling heart of San Francisco!

Check out Hotel Fiona, a charming family-friendly gem in San Francisco’s lively SoMa district! Known for its cozy Victorian vibe, this hotel is a fantastic spot for your next getaway. You’ll be sipping complimentary coffee or tea in the lobby each morning, ready to explore nearby museums, shops, and delicious eateries. Each room celebrates iconic figures of San Francisco’s history while offering free Wi-Fi, a smart TV, plush robes, and a coffee machine to keep you comfy and connected.

For some off-site fun, The Strand Theater is just a hop away, and if you’re cheering for the San Francisco Giants, it's a quick trip to AT&T Park! Need to cool off or break a sweat? You can access a heated outdoor pool and a fitness center at the hotel’s sister property just across the street. With lovely amenities and a friendly atmosphere, Hotel Fiona promises you a delightful San Francisco experience!

The San Francisco Marriott Marquis is a fantastic spot in the heart of downtown, right next to the Moscone Convention Center! Guests can enjoy luxurious, stylish rooms that come with huge flat-screen TVs, air conditioning, a minibar, and even tea and coffee-making goodies. If you're lucky, you might just snag a room with breathtaking views of the city!

Start your day with a delicious breakfast at B55 Craft House and Kitchen, where you can fuel up before hopping over to the nearby San Francisco Museum of Modern Art or taking a stroll to Union Square. After a fun-filled day, unwind in the hotel's fitness center and make it a memorable San Francisco adventure!

If you're looking for a top-notch place to stay in Mission Bay, check out Hotel Zetta San Francisco! This welcoming hotel is located right across from Westfield Shopping Center, perfect for shopping sprees or grabbing a quick bite. Each comfy room features a large flat-screen smart TV, an iPod docking station, and even a Bluetooth speaker. For a touch of luxury, enjoy your own Illy espresso machine and premium toiletries are readily available in your stylish bathroom.

Dine at The Cavalier Restaurant, where you can savor delicious UK-style dishes, and the full-service bar is just waiting for you to unwind after a fun day exploring the city. Don’t forget to work up a sweat at the fitness center, or hop into the games room for a little friendly competition. You’ll also be just a short walk from the buzz of Union Square and the Moscone Center, making it a great spot for fun and adventure in San Francisco!

The Mosser Hotel is a charming blend of history and modern comfort right in the heart of San Francisco. Built in 1913, this delightful hotel offers stylish rooms equipped with free WiFi, bathrobes, and hairdryers. Many rooms even come with their own private bathrooms and a selection of lovely bath amenities to make you feel right at home.

When you’re ready to refuel, head down to Keystone for some tasty American comfort food. With a cozy 12-seat communal table, it’s the perfect place to share a meal with friends or strike up a conversation with fellow travelers. Enjoy two happy hours and indulge in weekend brunch with unique drinks that’ll tickle your taste buds. Whether it's for a working trip or a leisurely escape, The Mosser gives you a warm, inviting experience in the vibrant city of San Francisco!

Hyatt Regency San Francisco Downtown SOMA is a fantastic spot for your stay in Mission Bay. This 4-star hotel combines comfort and convenience with air-conditioned rooms, a fitness center, and complimentary WiFi to keep you connected. You’ll feel right at home with well-equipped rooms featuring flat-screen TVs, cozy linens, and your own private bathroom. Plus, some rooms offer great views of the city!

When it’s time to eat, don’t miss out on La Societe Bar & Café. This acclaimed French restaurant serves up delicious breakfast, cocktails, and dinner, earning rave reviews from foodies everywhere. There’s also a lively on-site bar and a business area if you're here for work or just need a quiet place to catch up. With popular attractions like Moscone Center and Oracle Park nearby, your stay promises to be both fun and fulfilling!