When visiting Memphis for a stay near St. Jude Children's Research Hospital, you want the perfect home away from home. I’ve explored some fantastic hotels that not only offer comfort and convenience but also help you relax after a busy day. Whether you're here for a medical need or just to enjoy the vibrant culture of Memphis, this list will guide you to the best places to stay near St. Jude. Let’s dive in and find the perfect spot for your unforgettable trip!
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250 North Main Street | 0.4 mi (0.7km) to St. Jude Children's Research Hospital
Sheraton Memphis Downtown Hotel is an excellent choice for your stay near St. Jude. You’ll find yourself just steps away from the lively atmosphere of historic Beale Street, where music and fun await. Plus, there's a Main Street Trolley stop right outside, making it easy to hop on over to local attractions like the National Civil Rights Museum and the South Main Historic Arts District.
Each comfortable room at the Sheraton comes packed with handy amenities, including a flat-screen TV, a work space, and even some rooms with stunning views of the Mississippi River. When you get hungry, Crossroads Tavern & Grille has delicious Southern dishes and fancy cocktails waiting for you. The hotel also features a fitness center for you to keep up your routine, business facilities if you need to catch up on work, and even a snack shop to grab a quick bite or drink at any time. Enjoy your stay and all that Memphis has to offer!
22 North B.B. King Boulevard | 0.7 mi (1.2km) to St. Jude Children's Research Hospital
Looking for a great hotel near St. Jude in Memphis? Check out Hotel Indigo - Memphis Downtown, an IHG Hotel! This spot is all about comfort and convenience, offering cozy, air-conditioned rooms where you can relax. Take a dip in the seasonal outdoor pool, stay connected with free WiFi, or break a sweat at the fitness center. Plus, there’s a friendly vibe thanks to the 24-hour front desk and shared lounge. Don’t forget to treat yourself to some tasty American dishes at the on-site restaurant or unwind with a cocktail at the snack bar.
Each room is designed with your comfort in mind, featuring a flat-screen TV, a desk for any work you need to catch up on, and a private bathroom stocked with essentials like a hairdryer. You can start your day off right with a delicious à la carte or American breakfast. Got work to tackle? Their business center has you covered. Hotel Indigo places you close to some cool spots like the Fire Museum of Memphis, Orpheum Theater, and AutoZone Park, so there’s no shortage of fun nearby! Enjoy your visit to Memphis!
75 Jefferson Avenue | 0.7 mi (1.2km) to St. Jude Children's Research Hospital
Looking for a great hotel near St. Jude in Memphis? Check out the Courtyard Memphis Downtown! This welcoming spot offers comfy guest rooms that come with 32-inch flat-screen TVs and all the shows you love on cable. When you’re not relaxing in your room, soak your cares away in the hot tub or catch up with friends online with free Wi-Fi.
Each room at the Courtyard looks after your needs with handy extras like a refrigerator and coffee facilities. Plus, if you need to grab a snack or do a little laundry, they've got vending machines and laundry facilities right on site. Just a short walk away, you’ll find the charming Court Square Park and the lively Main Street Trolley, making it easy to explore everything Memphis has to offer. Enjoy your stay and make those memories!
40 North Front Street | 0.8 mi (1.2km) to St. Jude Children's Research Hospital
Looking for a cozy stay near St. Jude in Memphis? Check out Moxy Memphis Downtown! Located right in the vibrant heart of downtown, this fun hotel puts you close to all the excitement. Each guest room is equipped with a flat-screen TV for your entertainment and comfy amenities to make you feel right at home, including free Wi-Fi.
Want to stay active during your visit? There’s a fitness center where you can work up a sweat. Plus, if you need to get some work done, the business center is ready to help. Need to hold a small meeting? The conference room is perfect for up to 14 people. After a day of adventures, unwind and prepare for more Memphis exploration—you're going to love it here!
85 West Court Avenue | 0.8 mi (1.2km) to St. Jude Children's Research Hospital
Look no further for a comfy stay near St. Jude in Memphis! At SpringHill Suites Memphis Downtown, you'll find a welcoming atmosphere along with an outdoor pool and delightful complimentary breakfast to kickstart your day. The best part? You can easily stroll to Beale Street and hop on the trolley line at Court Square—fun is just around the corner!
Each stylish studio comes with free WiFi and handy amenities like a refrigerator and microwave for those late-night snacks. A flat-screen TV is perfect for cozy movie nights. Need to squeeze in a workout? There’s a fitness center waiting for you! Plus, the on-site laundry facilities make life a breeze during your stay. Get ready for a fabulous experience in Memphis!
179 Madison Avenue | 0.8 mi (1.3km) to St. Jude Children's Research Hospital
Hotel Napoleon brings you the heart of Memphis with a cozy vibe that's hard to beat. Just a short stroll takes you to AutoZone Park and the famous Beale Street, making it a perfect spot for catching some local music or enjoying tasty eats. Plus, the Memphis Rock 'n' Soul Museum is nearby, so dive into the rich culture right around the corner!
You'll love the rooms here, all equipped with flat-screen TVs for your entertainment. Each cozy space features a private bathroom with fluffy bathrobes and free goodies to pamper yourself. With air conditioning and a desk, you'll have everything you need for a comfy stay while discovering the city.
Don't miss out on the Orpheum Theater or FedExForum, both a quick walk away. Hotel Napoleon is your gateway to a fun-filled Memphis adventure!
50 Harbor Town Square | 0.8 mi (1.3km) to St. Jude Children's Research Hospital
Step into the charm of the River Inn of Harbor Town, where you'll be greeted with a refreshing glass of champagne right at check-in! This riverside boutique hotel, perched by the Mississippi, is perfect for guests seeking a unique Memphis experience. Enjoy a delicious breakfast at one of the three on-site restaurants before you head out to explore the city.
Each room boasts vintage European decor with a delightful four-poster bed, a flat-screen TV, and a handy refrigerator. Many rooms even offer stunning views of the river, adding a nice touch to your stay. With a rooftop terrace providing panoramic sights, savor gourmet eats at Paullette’s Restaurant or casual bites at Tugs Neighborhood Grill. Don’t forget to stay connected with the free Wi-Fi or take advantage of the fitness center whenever you wish!
Whether you're catching a show at the nearby Orpheum Theatre or making plans for a day at the Memphis Zoo, the River Inn of Harbor Town is your cozy hub for an unforgettable outing in Memphis. Happy travels!
79 Madison Avenue | 0.8 mi (1.3km) to St. Jude Children's Research Hospital
If you’re looking for a cozy place to stay in Memphis near St. Jude, you’re in for a treat! Check out the boutique hotel just a stone's throw from the vibrant Beale Street and the bustling riverfront. It's a great spot to unwind after a day of exploring, with comfy rooms featuring free WiFi, flat-screen TVs, and handy fridges for your snacks. Picture this: enjoying breakfast with a view of the Mississippi River from the rooftop space (though keep in mind it's closed on Sundays).
This hotel puts you right at the heart of the action, making it super easy to pop out and catch all that Memphis has to offer. So whether you’re gearing up for a thrilling night out or planning to tour local attractions, this charming spot serves as your perfect starting point. Happy adventures!
310 Union Avenue | 0.9 mi (1.4km) to St. Jude Children's Research Hospital
For a delightful stay in Memphis near St. Jude, La Quinta by Wyndham Memphis Downtown might just be your new favorite spot! With free WiFi available throughout the property, a handy fitness center, and complimentary parking for those who drive, it’s all about making you feel at home. You'll love the convenient location, close to famous sites like the Memphis Rock n Soul Museum and AutoZone Park. Plus, enjoy a tasty continental breakfast each morning to fuel your adventures!
The cozy rooms come with their own private bathrooms and you can unwind with a dip in the indoor pool or relax on the terrace. The friendly staff is always ready to help you navigate the local area and suggest the best things to see and do. Whether you’re here for the music scene or delicious BBQ, La Quinta makes it easy to enjoy everything Memphis has to offer. Enjoy your stay and make some fantastic memories!
110 Monroe Avenue | 0.9 mi (1.4km) to St. Jude Children's Research Hospital
When you're looking for a great hotel in Memphis near St. Jude, Residence Inn Memphis Downtown is a fantastic choice! With a sleek fitness center, cozy private parking, and a sunny terrace, it has all the essentials for a comfortable stay. You’ll be just a short walk from favorites like the Orpheum Theater and AutoZone Park, making it super easy to explore the local excitement.
The rooms are designed for relaxation and some even feature kitchens so you can whip up your own meals if you're feeling adventurous. Each morning, kickstart your day with a yummy buffet breakfast offering American, continental, or other delights. Friendly staff are there to help you with tips on exploring the city's vibrant music scene and tasty BBQ spots. Enjoy your stay and make lasting memories!
164 Union Avenue | 0.9 mi (1.5km) to St. Jude Children's Research Hospital
Looking for the best hotels in Memphis near St. Jude? Look no further than the Canopy By Hilton Memphis Downtown! Just a hop away from AutoZone Park, this fabulous hotel features a fantastic fitness center, private parking, and a delicious on-site restaurant and bar. With free WiFi and a helpful 24-hour front desk, it’s perfect for unwinding after a day of exploring all that Memphis has to offer.
The location couldn’t be better, with the city center and Orpheum Theater a short stroll away. You'll also find exciting spots like FedExForum and the Fire Museum of Memphis right around the corner. So grab your friends or family, and dive into a city full of music and culture. Enjoy your time at Canopy By Hilton, where great memories are waiting to be made!
201 Union Avenue | 0.9 mi (1.5km) to St. Jude Children's Research Hospital
If you're hunting for a cozy spot to relax in Memphis near St. Jude, check out the Hilton Garden Inn Memphis Downtown Beale Street. This friendly hotel has it all! Soak up the vibrant vibe in the shared lounge or enjoy a drink at the bar. With a tasty American restaurant on-site and complimentary WiFi, comfort and convenience are just steps away. Plus, you’re just a short walk from attractions like AutoZone Park and the Orpheum Theater.
The rooms here are designed for your comfort, featuring air conditioning, flat-screen TVs, and handy kitchenettes complete with microwaves and small refrigerators. Imagine sipping coffee from your own single-cup maker while safely tucked in with your belongings in the in-room safe! The welcoming front desk staff are ready to share the best local tips, making your stay even easier. Wind down with a cocktail at The Greyhound Bar or enjoy a meal at Seasons Grille, perfect for breakfast, dinner, or evening room service. Experience Memphis in style at the Hilton Garden Inn!
185 Union Avenue | 0.9 mi (1.5km) to St. Jude Children's Research Hospital
Looking for a great hotel in Memphis near St. Jude? The DoubleTree Hotel is just the spot! Nestled right in downtown, it's a fun base for your adventures. Right across the street, you can catch a Memphis Redbirds or 901 FC game at AutoZone Park. With famous Beale Street just a stroll away, you’ll have easy access to live music, tasty food, and local culture.
At DoubleTree, comfort is the name of the game. Each of their 280 smoke-free rooms has everything youneed for a fabulous stay—think cozy beds, flat-screen TVs, and even coffee & tea service to kickstart your mornings. Planning a meeting or a fun gathering? They have versatile spaces just for you! Plus, they welcome your furry friends, making it a perfect spot for everyone in the family. Enjoy your time in Memphis at the DoubleTree—it’s all about making great memories!
149 Union Avenue | 0.9 mi (1.5km) to St. Jude Children's Research Hospital
If you're on the lookout for a top-notch hotel in Memphis near St. Jude, look no further than The Peabody Hotel! Just a hop away from Beale Street, this historic gem blends Southern charm with upscale luxury. Enjoy fantastic amenities like an indoor pool, a fully-equipped fitness center, and even a spa to pamper yourself after a day of exploring.
The rooms are all about comfort and style, with roomy seating areas, plush robes, and flat-screen TVs to keep you entertained. When it comes to dining, you’ve got choices! Savor gourmet French dishes at Chez Philippe or dig into delightful Southern favorites at Capriccio Grill. For a more relaxed vibe, Peabody Corner Bar offers a cozy spot to unwind with food and drink specials. Staying here means you'll be right in the heart of the action, with local attractions like the Memphis Rock ‘n Soul Museum and the Gibson Guitar Factory all just a short stroll away. Grab your bags, and get ready for a memorable stay!
175 Peabody Place | 1.1 mi (1.7km) to St. Jude Children's Research Hospital
If you’re searching for a great place to stay in Memphis near St. Jude, the Hampton Inn & Suites Memphis-Beale Street is a fantastic choice. Located right in the heart of the downtown entertainment district, this hotel makes it easy to enjoy everything the city has to offer. Imagine waking up to a delicious complimentary breakfast every day and staying connected with free WiFi throughout your visit!
The rooms here are designed for comfort, featuring flat-screen TVs, workspaces, and cozy chairs. If you choose a suite, you get the extra perk of a separate living area, a microwave, and a refrigerator—perfect for snacking! Plus, there’s an indoor pool for a refreshing dip and a fitness center if you want to stay active. With friendly service and great amenities, this hotel is a delightful spot to put your feet up after exploring Memphis!
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Dan, a digital nomad with 10+ years of experience, has traveled to 55+ countries, sharing expert tips to help others find the best places to stay.
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Post was updated on May 16, 2025
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