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15 Top Hotels in Memphis near I-40

Welcome to Memphis, a city bursting with music, culture, and delicious BBQ! If you're hitting the road on I-40, I’ve got you covered with a list of 15 top hotels right off the highway. Each one offers cozy accommodations and easy access to all the Memphis fun, making it simple for you to unwind after a day of exploring. Let’s dive into these great options to find the perfect spot for your stay!

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La Quinta by Wyndham Memphis Downtown

La Quinta by Wyndham Memphis Downtown

Holiday Inn Express Memphis Medical Center - Midtown, An IHG Hotel

1180 Union Avenue | 0.9 mi (1.5km) to Interstate 40

8Very Good
Holiday Inn Express Memphis Medical Center - Midtown, an IHG Hotel ImageHoliday Inn Express Memphis Medical Center - Midtown, an IHG Hotel ImageHoliday Inn Express Memphis Medical Center - Midtown, an IHG Hotel Image

The Holiday Inn Express in Midtown Memphis is a cozy spot right by I-40 where comfort meets convenience. Start your day with a delicious hot breakfast buffet, and when you're ready to unwind, take a dip in the outdoor pool. Plus, you can stay connected with free WiFi throughout the hotel, making it perfect for both leisure and work.

Inside, you’ll find modern rooms with all the essentials, including a flat-screen TV and a coffee maker to brew your morning pick-me-up. There's a fitness room to keep you active, along with a welcoming space by the pool to relax. It’s a fantastic base for exploring Memphis, with popular spots like Beale Street and St. Jude Research Hospital just a short drive away.

La Quinta By Wyndham Memphis Downtown

310 Union Avenue | 1.2 mi (1.9km) to Interstate 40

8.6Excellent
La Quinta by Wyndham Memphis Downtown ImageLa Quinta by Wyndham Memphis Downtown ImageLa Quinta by Wyndham Memphis Downtown Image

La Quinta by Wyndham Memphis Downtown is the perfect place to kick back after a day of adventure in Memphis. Conveniently located in the city center, this hotel offers free WiFi and complimentary parking for guests. You can work off all that delicious Southern food in their fitness center or take a refreshing dip in the indoor pool. Don’t forget to start your mornings right with a tasty continental breakfast to fuel your day!

The rooms are cozy and equipped with everything you need, including your own private bathroom. Friendly staff at the reception are always ready to help with tips for exploring the area, from discovering the soulful vibes of the Memphis Rock n Soul Museum to enjoying live shows at the nearby FedExForum. La Quinta is a fantastic choice for anyone wanting to experience the rich culture of Memphis near I-40!

Sheraton Memphis Downtown Hotel

250 North Main Street | 1.3 mi (2km) to Interstate 40

7.5Good
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If you’re looking for a friendly place to stay in Memphis, check out the Sheraton Memphis Downtown Hotel! This full-service hotel puts you right near the buzz of Beale Street, and with a Main Street Trolley stop right outside, getting around town is a breeze. You can easily hop over to the National Civil Rights Museum or the lively South Main Historic Arts District for some sightseeing or fun.

Each cozy room at the Sheraton comes with a flat-screen TV and a comfy work area. Some even offer lovely views of the Mississippi River, making it a nice spot to relax. Ready to munch? The Crossroads Tavern & Grille has delicious Southern American dishes and crafted cocktails to sip on. Whether you want to hit the gym or have a meeting space ready, this hotel has you covered. Enjoy some snacks from the on-site shop while you unwind after a busy day exploring!

Hotel Indigo - Memphis Downtown, An IHG Hotel

22 North B.B. King Boulevard | 1.3 mi (2.1km) to Interstate 40

7.6Good
Hotel Indigo - Memphis Downtown, an IHG Hotel ImageHotel Indigo - Memphis Downtown, an IHG Hotel ImageHotel Indigo - Memphis Downtown, an IHG Hotel Image

If you're on the hunt for a great spot to crash in Memphis, Hotel Indigo - Memphis Downtown is the place to be! This gem right in the heart of the city has everything you need for a comfy stay. Enjoy fresh air by taking a dip in the seasonal outdoor pool, or keep your fitness routine going in their well-equipped gym. The lively atmosphere makes it the perfect place to kick back and enjoy some tasty bites at the restaurant or a refreshing drink at the snack bar.

Each air-conditioned room is cozy and comes with a flat-screen TV and a desk, making it a great fit for both relaxation and work. You can also start your day right with a delicious American breakfast before hitting the town. If you get the urge to explore, you'll find popular attractions like the Fire Museum of Memphis and Orpheum Theater just a hop away. Hotel Indigo is truly a welcoming spot where you can unwind and enjoy everything Memphis has to offer!

Hotel Napoleon Memphis

179 Madison Avenue | 1.3 mi (2.2km) to Interstate 40

7.8Good
Hotel Napoleon Memphis ImageHotel Napoleon Memphis ImageHotel Napoleon Memphis Image

When looking for a cozy place to stay in Memphis, Hotel Napoleon is a charming choice right in the heart of the city. You’re just minutes away from local highlights like AutoZone Park and Beale Street, making it easy to explore the vibrant area. Rooms are comfortable and equipped with everything you need, including a flat-screen TV, chic private bathroom, and desk. Plus, you’ll find air conditioning so you can relax after a day of adventures.

Feeling entertained? You're a short stroll from the iconic Orpheum Theater and the FedExForum, so there's always something happening nearby. After a fun day, you can unwind at the hotel and enjoy the friendly atmosphere. Hotel Napoleon is a fantastic spot where you can dive into all the Memphis excitement while having a lovely home base!

Hilton Garden Inn Memphis Downtown Beale Street

201 Union Avenue | 1.4 mi (2.2km) to Interstate 40

8.4Very Good
Hilton Garden Inn Memphis Downtown Beale Street ImageHilton Garden Inn Memphis Downtown Beale Street ImageHilton Garden Inn Memphis Downtown Beale Street Image

Looking for a comfy spot to unwind in Memphis? The Hilton Garden Inn Downtown Beale Street might just be your perfect match! Located conveniently close to the hustle and bustle, this hotel features a cozy lounge and a bar where you can kick back. With free Wi-Fi and a tasty American restaurant on-site, you’ll feel right at home.

Your room will be a welcoming retreat with air conditioning, a flat-screen TV, and a mini fridge for your snacks. You can even brew a cup of coffee whenever the mood strikes! When you need tips on local attractions, the friendly reception staff is ready to help make your stay even better. After a day of exploring, sip a cocktail at The Greyhound Bar or grab a meal at Seasons Grille. It’s all about comfort and convenience here!

DoubleTree By Hilton Memphis Downtown

185 Union Avenue | 1.4 mi (2.3km) to Interstate 40

7.4Good
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The Doubletree Hotel is a fantastic place to stay right in the heart of downtown Memphis. It’s just across from AutoZone Baseball Park, where you can catch exciting games featuring the Memphis Redbirds or the Memphis 901 FC soccer team. If you love being close to the action, this hotel puts you right in the mix!

Your comfort and safety are top priorities here. With comfy, smoke-free rooms that come loaded with free Wi-Fi, cable TV, and convenient coffee makers, you’ll have everything you need to relax. Plus, there's a full-service meeting space, a fun bar and restaurant, and if you’re traveling with your furry friend, you’re in luck—this hotel is pet-friendly! Enjoy a delightful stay and make the most of your Memphis adventure!

Courtyard Memphis Downtown

75 Jefferson Avenue | 1.4 mi (2.3km) to Interstate 40

8.1Very Good
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Discover a cozy gem in Memphis—the Courtyard Downtown! It’s the perfect spot to grab some rest after a fun day of exploring. Your room features a flat-screen TV with HBO, so you can kick back and unwind however you'd like. Want a snack or a late-night cup of coffee? Each room has a fridge and coffee maker, and there’s free Wi-Fi to keep you connected.

When you're ready for a little adventure, you're close to some local hotspots! The Gibson Retail Shop & Factory is just around the corner, and you're mere steps from the historic Court Square Park and Main Street Trolley. After a day of fun, take a dip in the hot tub to relax. Whether you're visiting for business or leisure, the Courtyard Downtown makes it easy to enjoy Memphis!

Canopy By Hilton Memphis Downtown

164 Union Avenue | 1.4 mi (2.3km) to Interstate 40

8.4Very Good
Canopy By Hilton Memphis Downtown ImageCanopy By Hilton Memphis Downtown ImageCanopy By Hilton Memphis Downtown Image

Nestled in the heart of Memphis, Canopy by Hilton Downtown is the perfect place to unwind and enjoy all that this vibrant city has to offer. With comfy rooms, a fitness center for those wanting to squeeze in a workout, and a stylish bar to kick back at, it’s got everything you need for a great stay! Plus, enjoy free Wi-Fi and friendly room service to make your experience even better.

You're just a stroll away from some fantastic spots like AutoZone Park and the famous Orpheum Theater, so you won't run out of fun activities. And for those who appreciate music and history, the nearby FedExForum and the Rock n Soul Museum will ignite your Memphis spirit. So, whether you’re here for fun or business, Canopy by Hilton is ready to welcome you with style!

SpringHill Suites Memphis Downtown

85 West Court Avenue | 1.4 mi (2.3km) to Interstate 40

8Very Good
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If you’re heading to Memphis and need a cozy spot to stay near I-40, check out SpringHill Suites Memphis Downtown! This charming hotel offers spacious studios with all the essentials, including a refrigerator, microwave, and even coffee facilities to fuel your adventures. And who doesn’t love a free breakfast? Start your day right before exploring the lively Beale Street, just a short walk away.

Make a splash at the outdoor pool and stay active with a workout in the gym. Whether you're on a work trip or enjoying a getaway, you’ll find amenities that make your stay super convenient, like on-site laundry and a business center. After a fun day visiting places like AutoZone Park, where you can catch a game, this hotel makes for a comfortable home base while you soak up the best of Memphis.

MOXY Memphis Downtown

40 North Front Street | 1.4 mi (2.3km) to Interstate 40

8.4Very Good
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If you're on the hunt for a comfy hotel near I-40 in Memphis, then Moxy Memphis Downtown is a great pick! Nestled right in the heart of downtown, you're just a hop away from must-see spots like the FedEx Forum, Orpheum Theatre, and the vibrant atmosphere of Beale Street. The cozy guest rooms come with free WiFi and flat-screen TVs, perfect for unwinding after a day of adventure. Plus, those little touches like hairdryers and complimentary bath goodies make your stay feel extra special.

While you're here, don’t miss out on some fun activities! Work up a sweat at the fitness center or huddle with friends in the hotel’s conference room, which has space for up to 14 people and comes equipped with a large flat-screen TV for all your presentations. Whether you're visiting the iconic Graceland or enjoying the buzzing nightlife, Moxy Memphis Downtown is an enjoyable spot to call home while you experience the charm of Memphis!

Peabody Memphis

149 Union Avenue | 1.5 mi (2.4km) to Interstate 40

8.7Excellent
Peabody Memphis ImagePeabody Memphis ImagePeabody Memphis Image

Just a short stroll from Beale Street, this charming hotel brings Southern hospitality to life with a touch of luxury. Guests can relax after a busy day in comfy rooms that include a flat-screen TV and plush bathrobes, plus a handy work desk for those who need to catch up on emails. Amenities like a serene indoor pool, a fitness center, and a full-service spa create the perfect atmosphere for a refreshing getaway.

When it comes to dining, you’re in for a treat! Chez Philippe offers delicious French cuisine served in a classy setting, while Capriccio Grill serves up Southern favorites like hearty steaks and fresh seafood. If you're in the mood for something more casual, Peabody Corner Bar is the ideal hangout for drinks and snack specials. With its beautiful rooftop space and views of the Mississippi River, this spot has everything you need for both fun and business. Enjoy your stay and soak up all that Memphis has to offer!

Residence Inn Memphis Downtown

110 Monroe Avenue | 1.5 mi (2.4km) to Interstate 40

9Exceptional
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Right in the heart of Memphis, Residence Inn Downtown offers a cozy stay with everything you need for a great visit. Just a short walk away from fun spots like the Orpheum Theater and AutoZone Park, this hotel makes exploring the city easy and enjoyable. With welcoming rooms that include a kitchen complete with a fridge, dishwasher, and microwave, you can eat in whenever you want. Plus, they'll start your day off right with a tasty breakfast that suits any craving.

When you're ready to unwind, make use of the fitness center or relax on the charming terrace. The hotel features helpful amenities like a friendly 24-hour front desk and convenient private parking. Whether you’re visiting for business or leisure, this hotel is the perfect home base to explore all the sights and sounds of Memphis! Enjoy your stay!

Hu Hotel Memphis

79 Madison Avenue | 1.5 mi (2.4km) to Interstate 40

8Very Good
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Step into a delightful stay at a lovely boutique hotel in Memphis that’s bursting with personality! Just a short walk from Memphis Riverboats and the iconic Mississippi River, you’ll find yourself in the center of the action. Take a stroll to Beale Street, where music and fun come alive.

Your room offers free WiFi, a cozy 32-inch flat-screen TV, and a fridge for all your snacks. Enjoy a delicious breakfast buffet when you’re ready to fuel up for the day. Don't forget to check out the rooftop area, where you can savor stunning panoramic views of the river—just keep in mind that it’s closed on Sundays.

With Memphis Central Station only a mile away, getting around is a breeze. Whether you're here for a getaway with friends or a peaceful retreat, this hotel offers everything you need for a fantastic stay in Memphis!

Hampton Inn & Suites Memphis-Beale Street

175 Peabody Place | 1.5 mi (2.5km) to Interstate 40

8.2Very Good
Hampton Inn & Suites Memphis-Beale Street ImageHampton Inn & Suites Memphis-Beale Street ImageHampton Inn & Suites Memphis-Beale Street Image

Experience a fun and friendly stay at the Hampton Inn & Suites Memphis-Beale Street! Nestled right in the heart of downtown Memphis, this hotel is perfect for those who love great food and easy access to the city’s vibrant entertainment. Start your day right with a complimentary breakfast and enjoy free WiFi throughout your stay. Each room comes equipped with a flat-screen TV, a cozy workspace, and, for those wanting a bit more space, spacious suites that include a separate living area, microwave, and refrigerator.

Don’t forget to take a dip in the indoor pool or break a sweat at the fitness center. If you need to get some work done, the hotel also features a business center and meeting rooms. After exploring the lively surroundings, unwind and enjoy your stay in this well-located hotel that’s perfect for exploring all that Memphis has to offer!

Dan Avramescu's profile

Dan Avramescu

Dan, a digital nomad with 10+ years of experience, has traveled to 55+ countries, sharing expert tips to help others find the best places to stay.

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Post was updated on May 27, 2025

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