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7 Top Hotels in Jacksonville near Museum Of Science and History (MOSH)

Jacksonville blends history, science, and fun, making it a perfect destination for curious travelers! Right next to the incredible Museum of Science and History (MOSH), these hotels offer the perfect home base for exploring this vibrant Florida city. We've carefully curated a list that ensures you'll find comfortable, convenient accommodations just steps away from one of Jacksonville's most fascinating attractions. Whether you're a solo traveler, family explorer, or business visitor, these hotels promise a memorable stay in the heart of Northeast Florida's coolest museum district.

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Our Pick

Hyatt Regency Jacksonville Riverfront

Hyatt Regency Jacksonville Riverfront

Southbank Hotel By Marriott Jacksonville Riverwalk

1515 Prudential Drive | 0.4 mi (0.6km) to MOSH

7.9Good
Southbank Hotel by Marriott Jacksonville Riverwalk ImageSouthbank Hotel by Marriott Jacksonville Riverwalk ImageSouthbank Hotel by Marriott Jacksonville Riverwalk Image

Situated along the St. Johns River in Jacksonville's vibrant San Marco district, Southbank Hotel offers contemporary rooms with river-view balconies, a fitness center, and Pier 1515 restaurant serving casual American cuisine. Just steps from the Museum of Science and History, the hotel provides convenient access to downtown attractions, a 24-hour business center, and a relaxing outdoor pool with a sundeck.

Amenities

1 swimming pool
Non-smoking rooms
Fitness centre
Facilities for disabled guests

Nearby

Cummer Museum of Art and Gardens
Jacksonville Museum of Modern Art
Jacksonville Historical Center
Jacksonville Maritime Museum Society

Important Info

Parking: USD 16/day
Free WiFi throughout
Pets allowed (on request)
Family friendly

Hyatt Regency Jacksonville Riverfront

225 East Coastline Drive | 0.4 mi (0.7km) to MOSH

8.5Excellent
Hyatt Regency Jacksonville Riverfront ImageHyatt Regency Jacksonville Riverfront ImageHyatt Regency Jacksonville Riverfront Image

Situated along the St. Johns River, this sleek Hyatt Regency offers stunning waterfront views, a rooftop pool, and three diverse dining options including SHOR Seafood Grill. The hotel provides modern amenities like free WiFi, a 24-hour fitness center, and a convenient city shuttle, making it an ideal base for exploring Jacksonville's vibrant downtown.

Amenities

1 swimming pool
Non-smoking rooms
Fitness centre
Facilities for disabled guests

Nearby

Cummer Museum of Art and Gardens
Jacksonville Museum of Modern Art
Florida Theatre
Jacksonville Maritime Museum Society

Important Info

Parking: USD 34/day
Free WiFi in rooms
Pets allowed (on request)
Family friendly

Marriott Jacksonville Downtown

245 Water Street | 0.5 mi (0.8km) to MOSH

8Very Good
Marriott Jacksonville Downtown ImageMarriott Jacksonville Downtown ImageMarriott Jacksonville Downtown Image

Located in downtown Jacksonville, this Marriott hotel offers modern rooms with Keurig® coffee machines, a 24-hour fitness center, and Juliette's Bistro serving American cuisine. Just steps from Jacksonville Landing and the Museum of Science and History, the property provides convenient access to local attractions with free WiFi and a welcoming concierge service.

Amenities

1 swimming pool
Non-smoking rooms
Fitness centre
Facilities for disabled guests

Nearby

Cummer Museum of Art and Gardens
Jacksonville Museum of Modern Art
Times-Union Center for the Performing Arts
Jacksonville Museum of Modern Art

Important Info

Parking: USD 36/day
WiFi: USD 9.95/hours
Pets allowed (charges apply)
Family friendly

Hilton Garden Inn Jacksonville Downtown Southbank

1201 Kings Avenue | 0.6 mi (0.9km) to MOSH

7.7Good
Hilton Garden Inn Jacksonville Downtown Southbank ImageHilton Garden Inn Jacksonville Downtown Southbank ImageHilton Garden Inn Jacksonville Downtown Southbank Image

Situated in downtown Jacksonville's vibrant Southbank district, this Hilton Garden Inn offers modern, well-appointed rooms with HBO-equipped flat-screen TVs and convenient amenities like an iPod docking station. The hotel provides guests with an on-site fitness center, business facilities, and an inviting outdoor pool with hot tub, making it an ideal choice for both leisure and business travelers exploring Jacksonville's attractions like MOSH and EverBank Field.

Amenities

1 swimming pool
Non-smoking rooms
Fitness centre
Facilities for disabled guests

Nearby

Cummer Museum of Art and Gardens
Jacksonville Museum of Modern Art
Jacksonville Historical Center
Alexander Brest Planetarium

Important Info

Parking: USD 20/day
Free WiFi throughout
Pets allowed (charges apply)
Family friendly

Homewood Suites By Hilton Jacksonville-Downtown/Southbank

1201 Kings Avenue | 0.6 mi (0.9km) to MOSH

8.1Very Good
Homewood Suites by Hilton Jacksonville-Downtown/Southbank ImageHomewood Suites by Hilton Jacksonville-Downtown/Southbank ImageHomewood Suites by Hilton Jacksonville-Downtown/Southbank Image

Centrally located in Downtown Jacksonville, this Homewood Suites offers spacious, modern rooms with flat-screen TVs, a fitness center, and an inviting outdoor pool perfect for relaxing after exploring nearby attractions. The hotel provides a complimentary buffet breakfast and convenient amenities like free WiFi and private parking, making it an ideal home base for museum and downtown adventures.

Amenities

1 swimming pool
Non-smoking rooms
Fitness centre
Facilities for disabled guests

Nearby

Cummer Museum of Art and Gardens
Jacksonville Museum of Modern Art
Jacksonville Historical Center
San Marco Theatre

Important Info

Parking: USD 20/day
Free WiFi throughout
Pets allowed (charges apply)
Family friendly

Residence Inn By Marriott Jacksonville Downtown

357 Oak Street | 1 mi (1.6km) to MOSH

8.9Excellent
Residence Inn by Marriott Jacksonville Downtown ImageResidence Inn by Marriott Jacksonville Downtown ImageResidence Inn by Marriott Jacksonville Downtown Image

Residence Inn by Marriott Jacksonville Downtown offers spacious studio-style suites with full kitchens, a complimentary buffet breakfast, and an outdoor pool perfect for relaxing near downtown attractions. Located steps from the Prime F. Osborn III Convention Center, this property provides convenient access to Jacksonville's cultural sites with modern amenities and comfortable, apartment-like accommodations.

Amenities

1 swimming pool
Non-smoking rooms
Fitness centre
Facilities for disabled guests

Nearby

Cummer Museum of Art and Gardens
Jacksonville Museum of Modern Art
Riverside Park
Cummer Museum of Art and Gardens

Important Info

Parking: USD 12/day
Family friendly

Home2 Suites By Hilton Jacksonville Downtown

600 Park Street | 1.1 mi (1.8km) to MOSH

8Very Good
Home2 Suites By Hilton Jacksonville Downtown ImageHome2 Suites By Hilton Jacksonville Downtown ImageHome2 Suites By Hilton Jacksonville Downtown Image

Home2 Suites By Hilton offers modern comfort in downtown Jacksonville, with spacious rooms featuring air conditioning, flat-screen TVs, and work desks. Guests enjoy complimentary breakfast, free parking, a fitness center, and convenient proximity to the Museum of Science and History and Florida Theatre.

Amenities

Non-smoking rooms
Fitness centre
Facilities for disabled guests
Family rooms

Nearby

Cummer Museum of Art and Gardens
Jacksonville Museum of Modern Art
Riverside Park
Cummer Museum of Art Library

Important Info

Parking available
Family friendly
Olga Melnikova's profile

Olga Melnikova

Olga, a hospitality graduate with 10+ years of experience in hotels and travel blogging, has explored Europe extensively and shares expert travel insights.

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Post was updated on July 22, 2025

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