Cincinnati's vibrant urban scene deserves the right accommodation to enhance your visit. After analyzing dozens of properties near 21c Museum Hotel, I've identified hotels that blend Midwest hospitality with easy access to the city's thriving arts district and riverside attractions. My research revealed fantastic options with varying amenities and price points. These hotels offer everything from rooftop views of the Ohio River to walking distance convenience to the Contemporary Arts Center and Fountain Square, ensuring you'll find the perfect Cincinnati base.
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609 Walnut Street | 0 mi (0km) to 21c Museum Hotel Cincinnati
This contemporary art hotel combines a vibrant gallery with elegant rooms featuring flat-screen TVs and modern furnishings. Guests enjoy the rooftop bar, farm-to-table restaurant, and prime location just steps from the Aronoff Center and minutes from Fountain Square.
617 Vine Street Suite A | 0.1 mi (0.2km) to 21c Museum Hotel Cincinnati
Positioned directly across from Fountain Square, Hampton Inn and Suites Cincinnati - Downtown combines prime location with essential amenities. Each contemporary room features an HDTV and coffee maker, while the hotel delivers with a 24-hour mini-market, state-of-the-art fitness center, and complimentary breakfast buffet.
21 East 5th Street | 0.2 mi (0.3km) to 21c Museum Hotel Cincinnati
Experience modern luxury at this Cincinnati Westin, featuring plush rooms with floor-to-ceiling windows and an on-site McCormick & Schmick's Seafood Restaurant. Steps from Fountain Square and the Great American Ball Park, the hotel provides convenient amenities including Wi-Fi, business services, and daily continental breakfast.
37 West 7th Street | 0.2 mi (0.3km) to 21c Museum Hotel Cincinnati
Centrally located in downtown Cincinnati, the 4-star Kinley Cincinnati Downtown offers stylish rooms with flat-screen TVs and fridges, plus on-site dining and a fitness center. The Tribute Portfolio Hotel provides convenient access to city highlights like Freedom Center and nearby stadiums, all while ensuring comfort with 24-hour service and free WiFi.
6 East 4th Street | 0.2 mi (0.3km) to 21c Museum Hotel Cincinnati
Located in downtown Cincinnati, Courtyard by Marriott offers modern rooms with flat-screen TVs just 200 meters from the city center. Guests enjoy easy access to top attractions including Freedom Center and Great American Ball Park, plus convenient amenities like an on-site restaurant, fitness center, and American breakfast service.
106 West 7th Street | 0.2 mi (0.3km) to 21c Museum Hotel Cincinnati
Located in Downtown Cincinnati just steps from the city center, TownePlace Suites offers modern accommodations within walking distance of Freedom Center. Sports fans will appreciate the proximity to Great American Ball Park and Paul Brown Stadium, while the property's convenient position provides easy access to Cincinnati's top cultural attractions.
36 East Fourth Street | 0.2 mi (0.3km) to 21c Museum Hotel Cincinnati
The Renaissance Cincinnati Downtown Hotel combines upscale comfort with prime location just steps from Freedom Center and major stadiums. Guests enjoy modern rooms with seating areas, cable TV, and well-appointed bathrooms, while the property features a fitness center, meeting spaces, and 24-hour service.
151 West FIfth Street | 0.3 mi (0.4km) to 21c Museum Hotel Cincinnati
Located in downtown Cincinnati, Hyatt Regency offers elegant rooms with flat-screen TVs and a prime location just steps from major stadiums. Guests enjoy access to the indoor pool, 24-hour fitness center, and convenient dining options at Red Roost Tavern and The Market.
506 East 4th Street | 0.4 mi (0.7km) to 21c Museum Hotel Cincinnati
Just steps from Cincinnati's top attractions, Residence Inn Downtown offers spacious rooms with fully-equipped kitchens, HBO, and free Wi-Fi. Guests enjoy a hot continental breakfast, convenient on-site bar, and fitness center while being only minutes from the Zoo, Art Museum, and major sports venues.
701 Broadway Street | 0.5 mi (0.7km) to 21c Museum Hotel Cincinnati
Located just steps from the city's cultural attractions, Voco The Clair Cincinnati Downtown combines modern comfort with convenience. The hotel boasts an indoor pool, fitness center, and on-site restaurant with bar, all while offering free WiFi and buffet breakfast for a seamless downtown stay.
135 Joe Nuxhall Way | 0.5 mi (0.7km) to 21c Museum Hotel Cincinnati
Perfectly positioned near Great American Ball Park and downtown attractions, AC Hotel by Marriott Cincinnati at The Banks offers modern rooms with flat-screen TVs and stylish bathrooms. Guests enjoy daily buffet breakfast, an on-site restaurant, fitness center, and convenient access to hiking trails, fishing spots, and Cincinnati's cultural landmarks.
311 Pike Street | 0.5 mi (0.8km) to 21c Museum Hotel Cincinnati
The Lytle Park Hotel pairs elegant accommodations with thoughtful amenities like a fitness center, terrace, and restaurant serving American and Italian cuisine. Just steps from Cincinnati attractions including Freedom Center and Great American Ball Park, this Autograph Collection property delivers comfort with luxurious rooms featuring upscale bathrobes and satellite TV.
610 Eden Park Drive | 1.2 mi (2km) to 21c Museum Hotel Cincinnati
Located just 3 km from Freedom Center, SpringHill Suites Midtown offers complimentary bikes, an indoor pool, and free WiFi in a modern setting. Guests enjoy buffet breakfast options, fitness center access, and 24-hour service in this comfortable 3-star property.
2500 South Market Street | 1.7 mi (2.8km) to 21c Museum Hotel Cincinnati
Just steps from Cincinnati University and 2.2 km from the Zoo, Fairfield Inn & Suites offers a refreshing indoor pool and modern fitness center. The 3-star property provides complimentary WiFi, comfortable accommodations, and convenient access to Cincinnati's cultural attractions like Museum Center and Freedom Center.
3024 Vine Street | 2.2 mi (3.5km) to 21c Museum Hotel Cincinnati
Just steps from the University of Cincinnati, this spacious Hampton Inn offers rooms with 37-inch flat-screen TVs and free WiFi. Guests enjoy a complimentary buffet breakfast, indoor pool, and quick access to Cincinnati Zoo and Medical College.
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Dan, a digital nomad with 10+ years of experience, has traveled to 55+ countries, sharing expert tips to help others find the best places to stay.
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Post was updated on June 3, 2025
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