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15 Top Hotels in Cincinnati near 21c Museum Hotel

Cincinnati's vibrant urban scene deserves the right accommodation to enhance your visit. After analyzing dozens of properties near 21c Museum Hotel, I've identified hotels that blend Midwest hospitality with easy access to the city's thriving arts district and riverside attractions. My research revealed fantastic options with varying amenities and price points. These hotels offer everything from rooftop views of the Ohio River to walking distance convenience to the Contemporary Arts Center and Fountain Square, ensuring you'll find the perfect Cincinnati base.

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Hyatt Regency Cincinnati

Hyatt Regency Cincinnati

21c Museum Hotel Cincinnati

609 Walnut Street | 0 mi (0km) to 21c Museum Hotel Cincinnati

8.4Very Good
21c Museum Hotel Cincinnati Image21c Museum Hotel Cincinnati Image21c Museum Hotel Cincinnati Image

This contemporary art hotel combines a vibrant gallery with elegant rooms featuring flat-screen TVs and modern furnishings. Guests enjoy the rooftop bar, farm-to-table restaurant, and prime location just steps from the Aronoff Center and minutes from Fountain Square.

Hampton Inn And Suites Cincinnati - Downtown

617 Vine Street Suite A | 0.1 mi (0.2km) to 21c Museum Hotel Cincinnati

7.3Good
Hampton Inn and Suites Cincinnati - Downtown ImageHampton Inn and Suites Cincinnati - Downtown ImageHampton Inn and Suites Cincinnati - Downtown Image

Positioned directly across from Fountain Square, Hampton Inn and Suites Cincinnati - Downtown combines prime location with essential amenities. Each contemporary room features an HDTV and coffee maker, while the hotel delivers with a 24-hour mini-market, state-of-the-art fitness center, and complimentary breakfast buffet.

The Westin Cincinnati

21 East 5th Street | 0.2 mi (0.3km) to 21c Museum Hotel Cincinnati

7.9Good
The Westin Cincinnati ImageThe Westin Cincinnati ImageThe Westin Cincinnati Image

Experience modern luxury at this Cincinnati Westin, featuring plush rooms with floor-to-ceiling windows and an on-site McCormick & Schmick's Seafood Restaurant. Steps from Fountain Square and the Great American Ball Park, the hotel provides convenient amenities including Wi-Fi, business services, and daily continental breakfast.

Kinley Cincinnati Downtown, A Tribute Portfolio Hotel

37 West 7th Street | 0.2 mi (0.3km) to 21c Museum Hotel Cincinnati

8.3Very Good
Kinley Cincinnati Downtown, a Tribute Portfolio Hotel ImageKinley Cincinnati Downtown, a Tribute Portfolio Hotel ImageKinley Cincinnati Downtown, a Tribute Portfolio Hotel Image

Centrally located in downtown Cincinnati, the 4-star Kinley Cincinnati Downtown offers stylish rooms with flat-screen TVs and fridges, plus on-site dining and a fitness center. The Tribute Portfolio Hotel provides convenient access to city highlights like Freedom Center and nearby stadiums, all while ensuring comfort with 24-hour service and free WiFi.

Courtyard By Marriott Cincinnati Downtown

6 East 4th Street | 0.2 mi (0.3km) to 21c Museum Hotel Cincinnati

8.1Very Good
Courtyard by Marriott Cincinnati Downtown ImageCourtyard by Marriott Cincinnati Downtown ImageCourtyard by Marriott Cincinnati Downtown Image

Located in downtown Cincinnati, Courtyard by Marriott offers modern rooms with flat-screen TVs just 200 meters from the city center. Guests enjoy easy access to top attractions including Freedom Center and Great American Ball Park, plus convenient amenities like an on-site restaurant, fitness center, and American breakfast service.

TownePlace Suites By Marriott Cincinnati Downtown

106 West 7th Street | 0.2 mi (0.3km) to 21c Museum Hotel Cincinnati

8.7Excellent
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Located in Downtown Cincinnati just steps from the city center, TownePlace Suites offers modern accommodations within walking distance of Freedom Center. Sports fans will appreciate the proximity to Great American Ball Park and Paul Brown Stadium, while the property's convenient position provides easy access to Cincinnati's top cultural attractions.

Renaissance Cincinnati Downtown Hotel

36 East Fourth Street | 0.2 mi (0.3km) to 21c Museum Hotel Cincinnati

8.1Very Good
Renaissance Cincinnati Downtown Hotel ImageRenaissance Cincinnati Downtown Hotel ImageRenaissance Cincinnati Downtown Hotel Image

The Renaissance Cincinnati Downtown Hotel combines upscale comfort with prime location just steps from Freedom Center and major stadiums. Guests enjoy modern rooms with seating areas, cable TV, and well-appointed bathrooms, while the property features a fitness center, meeting spaces, and 24-hour service.

Hyatt Regency Cincinnati

151 West FIfth Street | 0.3 mi (0.4km) to 21c Museum Hotel Cincinnati

8.3Very Good
Hyatt Regency Cincinnati ImageHyatt Regency Cincinnati ImageHyatt Regency Cincinnati Image

Located in downtown Cincinnati, Hyatt Regency offers elegant rooms with flat-screen TVs and a prime location just steps from major stadiums. Guests enjoy access to the indoor pool, 24-hour fitness center, and convenient dining options at Red Roost Tavern and The Market.

Residence Inn By Marriott Cincinnati Downtown/The Phelps

506 East 4th Street | 0.4 mi (0.7km) to 21c Museum Hotel Cincinnati

9Exceptional
Residence Inn by Marriott Cincinnati Downtown/The Phelps ImageResidence Inn by Marriott Cincinnati Downtown/The Phelps ImageResidence Inn by Marriott Cincinnati Downtown/The Phelps Image

Just steps from Cincinnati's top attractions, Residence Inn Downtown offers spacious rooms with fully-equipped kitchens, HBO, and free Wi-Fi. Guests enjoy a hot continental breakfast, convenient on-site bar, and fitness center while being only minutes from the Zoo, Art Museum, and major sports venues.

Voco The Clair Cincinnati Downtown, An IHG Hotel

701 Broadway Street | 0.5 mi (0.7km) to 21c Museum Hotel Cincinnati

8.7Excellent
Voco The Clair Cincinnati Downtown, an IHG Hotel ImageVoco The Clair Cincinnati Downtown, an IHG Hotel ImageVoco The Clair Cincinnati Downtown, an IHG Hotel Image

Located just steps from the city's cultural attractions, Voco The Clair Cincinnati Downtown combines modern comfort with convenience. The hotel boasts an indoor pool, fitness center, and on-site restaurant with bar, all while offering free WiFi and buffet breakfast for a seamless downtown stay.

AC Hotel By Marriott Cincinnati At The Banks

135 Joe Nuxhall Way | 0.5 mi (0.7km) to 21c Museum Hotel Cincinnati

8.8Excellent
AC Hotel by Marriott Cincinnati at The Banks ImageAC Hotel by Marriott Cincinnati at The Banks ImageAC Hotel by Marriott Cincinnati at The Banks Image

Perfectly positioned near Great American Ball Park and downtown attractions, AC Hotel by Marriott Cincinnati at The Banks offers modern rooms with flat-screen TVs and stylish bathrooms. Guests enjoy daily buffet breakfast, an on-site restaurant, fitness center, and convenient access to hiking trails, fishing spots, and Cincinnati's cultural landmarks.

The Lytle Park Hotel, Autograph Collection

311 Pike Street | 0.5 mi (0.8km) to 21c Museum Hotel Cincinnati

9.4Exceptional
The Lytle Park Hotel, Autograph Collection ImageThe Lytle Park Hotel, Autograph Collection ImageThe Lytle Park Hotel, Autograph Collection Image

The Lytle Park Hotel pairs elegant accommodations with thoughtful amenities like a fitness center, terrace, and restaurant serving American and Italian cuisine. Just steps from Cincinnati attractions including Freedom Center and Great American Ball Park, this Autograph Collection property delivers comfort with luxurious rooms featuring upscale bathrobes and satellite TV.

SpringHill Suites By Marriott Cincinnati Midtown

610 Eden Park Drive | 1.2 mi (2km) to 21c Museum Hotel Cincinnati

8.3Very Good
SpringHill Suites by Marriott Cincinnati Midtown ImageSpringHill Suites by Marriott Cincinnati Midtown ImageSpringHill Suites by Marriott Cincinnati Midtown Image

Located just 3 km from Freedom Center, SpringHill Suites Midtown offers complimentary bikes, an indoor pool, and free WiFi in a modern setting. Guests enjoy buffet breakfast options, fitness center access, and 24-hour service in this comfortable 3-star property.

Fairfield Inn & Suites By Marriott Cincinnati Uptown/University Area

2500 South Market Street | 1.7 mi (2.8km) to 21c Museum Hotel Cincinnati

8.6Excellent
Fairfield Inn & Suites by Marriott Cincinnati Uptown/University Area ImageFairfield Inn & Suites by Marriott Cincinnati Uptown/University Area ImageFairfield Inn & Suites by Marriott Cincinnati Uptown/University Area Image

Just steps from Cincinnati University and 2.2 km from the Zoo, Fairfield Inn & Suites offers a refreshing indoor pool and modern fitness center. The 3-star property provides complimentary WiFi, comfortable accommodations, and convenient access to Cincinnati's cultural attractions like Museum Center and Freedom Center.

Hampton Inn & Suites Cincinnati / Uptown - University Area

3024 Vine Street | 2.2 mi (3.5km) to 21c Museum Hotel Cincinnati

8Very Good
Hampton Inn & Suites Cincinnati / Uptown - University Area ImageHampton Inn & Suites Cincinnati / Uptown - University Area ImageHampton Inn & Suites Cincinnati / Uptown - University Area Image

Just steps from the University of Cincinnati, this spacious Hampton Inn offers rooms with 37-inch flat-screen TVs and free WiFi. Guests enjoy a complimentary buffet breakfast, indoor pool, and quick access to Cincinnati Zoo and Medical College.

Dan Avramescu's profile

Dan Avramescu

Dan, a digital nomad with 10+ years of experience, has traveled to 55+ countries, sharing expert tips to help others find the best places to stay.

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Post was updated on June 3, 2025

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